Laminin - Metabolism
Research News and Information

Sunday, November 22, 2009

Visual impairment in the absence of dystroglycan.

19 Oct 2009 Ocular involvement in muscular dystrophy ranges from structural defects to abnormal electroretinograms. While the mechanisms underlying the abnormal retinal physiology in patients are not understood, it is thought that alpha-dystroglycan ... Read more...

STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro.

13 Oct 2009 Nasopharyngeal cancer (NPC) is an Epstein-Barr virus (EBV)-associated head and neck cancer prevalent in Asia. Although with reasons not fully understood, the intrinsic invasiveness of NPC is believed to be EBV-linked. Recently, EBV was found to ... Read more...

Plasminogen enhances neuritogenesis on laminin-1.

5 Oct 2009 Proteins of the plasminogen activation system are broadly expressed throughout the nervous system, and key roles for these proteins in neuronal function have been demonstrated. Recent reports have established that plasminogen is synthesized in ... Read more...

Latest indexed articles for 'Laminin - Metabolism'

These are the very latest articles for this heading:

• Visual impairment in the absence of dystroglycan. 19 Oct 2009
• STAT3 activation contributes directly to Epstein-Barr virus-mediated invasiveness of nasopharyngeal cancer cells in vitro. 13 Oct 2009
• Plasminogen enhances neuritogenesis on laminin-1. 5 Oct 2009
• Vascular endothelial growth factor receptor-1 (VEGFR-1) expression in human corneal fibroblast decreased with age. 27 Sep 2009
• Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte development. 21 Sep 2009
• Anti-endoglin monoclonal antibodies are effective for suppressing metastasis and the primary tumors by targeting tumor vasculature. 13 Sep 2009
• Age-dependent changes in the gut environment restrict the invasion of the hindgut by enteric neural progenitors. 30 Aug 2009
• B-type natriuretic peptide enhances vasculogenesis by promoting number and functional properties of early endothelial progenitor cells. 30 Aug 2009
• Disruption of the cytoskeleton during Semaphorin 3A induced growth cone collapse correlates with differences in actin organization and associated binding proteins. 30 Aug 2009
• Identification of integrins alpha6 and beta7 as c-Jun- and transformation-relevant genes in highly invasive fibrosarcoma cells. 30 Aug 2009
• Borrelia burgdorferi BmpA is a laminin-binding protein. 22 Aug 2009
• Overexpression of beta3/gamma2 chains of laminin-5 and MMP7 in biliary cancer. 19 Aug 2009
• High molecular weight kininogen binds to laminin--characterization and kinetic analysis. 17 Aug 2009
• beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. 16 Aug 2009
• PI3K, Rho, and ROCK play a key role in hypoxia-induced ATP release and ATP-stimulated angiogenic responses in pulmonary artery vasa vasorum endothelial cells. 12 Aug 2009
• Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development. 8 Aug 2009
• A novel protein associated with membrane-type 1 matrix metalloproteinase binds p27(kip1) and regulates RhoA activation, actin remodeling, and matrigel invasion. 2 Aug 2009
• Mutagenesis at the alpha-beta interface impairs the cleavage of the dystroglycan precursor. 2 Aug 2009
• A role for pericytes as microenvironmental regulators of human skin tissue regeneration. Aug 2009
• Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Laminin'

Definition: Large, noncollagenous glycoprotein with antigenic properties. It is localized in the basement membrane lamina lucida and functions to bind epithelial cells to the basement membrane. Evidence suggests that the protein plays a role in tumor invasion.

Registry Number: 0

Descriptor UI: D007797

Alternative terms: Laminin; Glycoprotein GP-2; Glycoprotein GP 2; Merosin; Laminin M; Laminin M Chain; Chain, Laminin M; M Chain, Laminin;

Related Mesh Headings: Receptors, Laminin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.395.550.530; D12.776.543.550.500; D12.776.860.300.675;

History Note: 84

Technical Notes: an extracellular matrix protein; /biosyn /physiol permitted