Lentivirus - Physiology
Research News and Information

Monday, November 23, 2009

Lentivirus production.

30 Sep 2009 RNA interference (RNAi) is a system of gene silencing in living cells. In RNAi, genes homologous in sequence to short interfering RNAs (siRNA) are silenced at the post-transcriptional state. Short hairpin RNAs, precursors to siRNA, can be expressed ... Read more...

Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain.

28 Apr 2009 To understand how brain states and behaviors are generated by neural circuits, it would be useful to be able to perturb precisely the activity of specific cell types and pathways in the nonhuman primate nervous system. We used lentivirus to target ... Read more...

Host cell-specific effects of lentiviral accessory proteins on the eukaryotic cell cycle progression.

30 Mar 2009 Lentiviral accessory proteins are thought to play important roles in regulating the viral replication through modulation of host cell functions. For example, Vpr of human immunodeficiency virus type 1 (HIV-1) induces the cell cycle G2 arrest in a ... Read more...

Latest indexed articles for 'Lentivirus - Physiology'

These are the very latest articles for this heading:

• Lentivirus production. 30 Sep 2009
• Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. 28 Apr 2009
• Host cell-specific effects of lentiviral accessory proteins on the eukaryotic cell cycle progression. 30 Mar 2009
• Tricalcium phosphate nanoparticles enable rapid purification, increase transduction kinetics, and modify the tropism of mammalian viruses. 27 Feb 2009
• Transcription factor binding sites are genetic determinants of retroviral integration in the human genome. 22 Feb 2009
• Advantages of COS-1 monkey kidney epithelial cells as packaging host for small-volume production of high-quality recombinant lentiviruses. 12 Jan 2009
• Detection of replication competent retrovirus and lentivirus. 30 Dec 2008
• Protective antiviral immunity conferred by a nonintegrative lentiviral vector-based vaccine. 17 Dec 2008
• Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1. 29 Nov 2008
• The application of viral vectors to enhance regeneration after peripheral nerve repair. 29 Nov 2008
• Non-viral gene transfer by nucleofection allows stable gene expression in human neural progenitor cells. 17 Nov 2008
• The antiretroviral potency of APOBEC1 deaminase from small animal species. 27 Oct 2008
• Implication of the JNK pathway in a rat model of Huntington's disease. 26 Oct 2008
• Long-term reversal of cholinergic neuronal decline in aged non-human primates by lentiviral NGF gene delivery. 23 Oct 2008
• Turning astrocytes from the rostral migratory stream into neurons: a role for the olfactory sensory organ. 20 Oct 2008
• STAT3 silencing with lentivirus inhibits growth and induces apoptosis and differentiation of U251 cells. 5 Oct 2008
• Prophylaxis of graft-versus-host disease by lentiviral-mediated expression of herpes simplex virus-thymidine kinase and ganciclovir treatment. 29 Sep 2008
• Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry. 22 Sep 2008
• A rapid and efficient branched DNA hybridization assay to titer lentiviral vectors. 28 Aug 2008
• Quantitative analysis of retroviral and lentiviral gene transfer to murine embryonic stem cells. 7 Aug 2008

See a longer list of these articles.

Technical information about 'Lentivirus'

Definition: A genus of the family RETROVIRIDAE consisting of non-oncogenic retroviruses that produce multi-organ diseases characterized by long incubation periods and persistent infection. Lentiviruses are unique in that they contain open reading frames (ORFs) between the pol and env genes and in the 3' env region. Five serogroups are recognized, reflecting the mammalian hosts with which they are associated. HIV-1 is the type species.

Descriptor UI: D016086

Alternative terms: Lentivirus; Lentiviruses; Lentivirinae;

Allowable Qualifiers: classification; drug effects; enzymology; genetics; growth & development; immunology; isolation & purification; metabolism; pathogenicity; physiology; radiation effects; ultrastructure; chemistry;

Tree Number: B04.820.650.589; B04.909.777.731.589;

Online Note: use LENTIVIRUS to search LENTIVIRINAE 1991-93

History Note: 94; was LENTIVIRINAE 1991-93

Technical Notes: a genus of the family Retroviridae; Latin lenti-, slow, refers to its long incubation period; infection = LENTIVIRUS INFECTIONS