Lipodystrophy, Familial Partial - Pathology
Research News and Information

Sunday, November 22, 2009

Predicting abdominal adipose tissue among women with familial partial lipodystrophy.

30 May 2009 The objective of the study was to determine correlations between magnetic resonance imaging (MRI) measures of truncal adiposity (trunk fat percentage [TrF %(MRI)], visceral adipose tissue [VAT], and subcutaneous abdominal adipose tissue [SAT]), ... Read more...

The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation.

3 Feb 2009 We investigated the role of LMNA in adipose tissue by developing a novel mouse model of lipodystrophy. Transgenic mice were generated that express the LMNA mutation that causes familial partial lipodystrophy of the Dunnigan type (FPLD2). The ... Read more...

Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy.

17 Sep 2008 BACKGROUND: Type 2 familial partial lipodystrophy (FPLD2) is characterised by loss of fat in the limbs and buttocks and results from mutations in the LMNA gene. AIM: To evaluate the role of several genes involved in adipogenesis in order to better ... Read more...

Latest indexed articles for 'Lipodystrophy, Familial Partial - Pathology'

These are the very latest articles for this heading:

• Predicting abdominal adipose tissue among women with familial partial lipodystrophy. 30 May 2009
• The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation. 3 Feb 2009
• Site-dependent differences in both prelamin A and adipogenic genes in subcutaneous adipose tissue of patients with type 2 familial partial lipodystrophy. 17 Sep 2008
• Efficacy of pioglitazone in familial partial lipodystrophy of the Dunnigan type: a case report. 21 Oct 2007
• Peroxisome proliferator-activated receptor-gamma C190S mutation causes partial lipodystrophy. 11 Mar 2007
• Muscle and nerve pathology in Dunnigan familial partial lipodystrophy. 25 Feb 2007

See a longer list of these articles.

Technical information about 'Lipodystrophy, Familial Partial'

Definition: Inherited conditions characterized by the partial loss of ADIPOSE TISSUE, either confined to the extremities with normal or increased fat deposits on the face, neck and trunk (type 1), or confined to the loss of SUBCUTANEOUS FAT from the limbs and trunk (type 2).

Descriptor UI: D052496

Alternative terms: Lipodystrophy, Familial Partial; Familial Partial Lipodystrophies; Lipodystrophies, Familial Partial; Partial Lipodystrophies, Familial; Partial Lipodystrophy, Familial; Koberling-Dunnigan Syndrome; Koberling Dunnigan Syndrome; Familial Partial Lipodystrophy; Familial Partial Lipodystrophy, Type 2; Lipodystrophy, Familial Partial, Dunnigan Type; Dunnigan Syndrome; Syndrome, Dunnigan; Lipodystrophy, Familial Partial, Type 2; Familial Partial Lipodystrophy, Type 3; Lipodystrophy, Familial Partial, Type 3; Familial Partial Lipodystrophy, Type 1; Familial Partial Lipodystrophy, Kobberling Type; Lipodystrophy, Familial Partial, Type 1;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C17.800.849.391.700; C18.452.584.625.700; C18.452.880.391.700;

History Note: 2007; use DIABETES MELLITUS, LIPOATROPHIC 2005-2006