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Lipoproteins - Drug effects
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Definition of 'Lipoproteins'

Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins (CHYLOMICRONS; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol.

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Sunday, November 22, 2009

Antihypertensive treatment and its implications on lipoprotein metabolism of patients in care by a hypertension and diabetes program in Brazil.

22 Mar 2009 Multiple risk factors for cardiovascular disorders, particularly hypercholesterolemia, are often present in hypertensive patients. Several studies have shown that antihypertensive drugs affect the lipid profile, increasing the risk of cardiovascular ... Read more...


Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy.

21 Feb 2009 BACKGROUND: Niacin has multiple lipoprotein effects that may provide cardiovascular benefit when added to statin monotherapy. METHODS: In this randomized, placebo-controlled trial (n = 75) of magnetic resonance imaging of carotid atherosclerosis, we ... Read more...


[The impact of a new low dose oral contraceptive containing drospirenone on lipid profile, carbohydrate metabolism and hepatic function]

30 Jan 2009 INTRODUCTION: Application of older generations of progestins used in oral contraceptives may increase the risk of cardiovascular diseases (CVD) because of negative impact on lipids parameters. Drospirenone is a unique progestin that blocks the ... Read more...

 

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Technical information about 'Lipoproteins'

Definition: Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins (CHYLOMICRONS; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol.

Registry Number: 0

Descriptor UI: D008074

Alternative terms: Lipoproteins; Circulating Lipoproteins; Lipoproteins, Circulating; Lipoprotein;

Related Mesh Headings: Apolipoproteins; Hyperlipoproteinemias; Hypolipoproteinemias; Lipoid Proteinosis of Urbach and Wiethe; Proteolipids; Receptors, Lipoprotein;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D10.532; D12.776.521;

Technical Notes: general or unspecified; prefer specifics; /blood: consider also HYPERLIPOPROTEINEMIA; /defic: consider also HYPOLIPOPROTEINEMIAS & specifics

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