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Lipoproteins - Drug effects
Research News and Information
Definition of 'Lipoproteins'Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins (CHYLOMICRONS; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol. |
Sunday, November 22, 2009
22 Mar 2009
Multiple risk factors for cardiovascular disorders, particularly hypercholesterolemia, are often present in hypertensive patients. Several studies have shown that antihypertensive drugs affect the lipid profile, increasing the risk of cardiovascular ... Read more...
21 Feb 2009
BACKGROUND: Niacin has multiple lipoprotein effects that may provide cardiovascular benefit when added to statin monotherapy. METHODS: In this randomized, placebo-controlled trial (n = 75) of magnetic resonance imaging of carotid atherosclerosis, we ... Read more...
30 Jan 2009
INTRODUCTION: Application of older generations of progestins used in oral contraceptives may increase the risk of cardiovascular diseases (CVD) because of negative impact on lipids parameters. Drospirenone is a unique progestin that blocks the ... Read more...
Latest indexed articles for 'Lipoproteins - Drug effects'
These are the very latest articles for this heading:
- Antihypertensive treatment and its implications on lipoprotein metabolism of patients in care by a hypertension and diabetes program in Brazil.
22 Mar 2009 - Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy.
21 Feb 2009 - [The impact of a new low dose oral contraceptive containing drospirenone on lipid profile, carbohydrate metabolism and hepatic function]
30 Jan 2009 - Pleiotropic effects of fenofibrate.
30 Dec 2008 - Effects of hormonal treatment on lipids in patients with cancer.
12 Nov 2008 - Effect of mycolic acid on surface activity of binary surfactant lipid monolayers.
8 Oct 2008 - Hypolipidaemic mechanisms of action of CM108 (a flavone derivative) in hyperlipidaemic rats.
30 Aug 2008 - Chlordecone, a mixed pregnane X receptor (PXR) and estrogen receptor alpha (ERalpha) agonist, alters cholesterol homeostasis and lipoprotein metabolism in C57BL/6 mice.
24 Aug 2008 - Biomarkers and coagulation tests for assessing the biosimilarity of a generic low-molecular-weight heparin: results of a study in healthy subjects with enoxaparin.
18 Aug 2008 - Effects of adding prescription omega-3 acid ethyl esters to simvastatin (20 mg/day) on lipids and lipoprotein particles in men and women with mixed dyslipidemia.
20 May 2008 - Carbohydrate restriction and dietary cholesterol distinctly affect plasma lipids and lipoprotein subfractions in adult guinea pigs.
18 May 2008 - Depot-medroxyprogesterone acetate: an update.
8 May 2008 - The influence of supplemental lutein and docosahexaenoic acid on serum, lipoproteins, and macular pigmentation.
29 Apr 2008 - The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men.
16 Apr 2008 - Fish oil in the treatment of dyslipidemia.
30 Mar 2008 - Targeting cardiovascular risk in patients with diabetes: management of dyslipidemia.
30 Mar 2008 - Downregulation of hepatic lipoprotein assembly in rats by fermented products of Monascus pilosus.
15 Mar 2008 - Chlordecone altered hepatic disposition of [14C]cholesterol and plasma cholesterol distribution but not SR-BI or ABCG8 proteins in livers of C57BL/6 mice.
4 Feb 2008 - Meta-analysis: metformin treatment in persons at risk for diabetes mellitus.
30 Jan 2008 - Lipid management to reduce cardiovascular risk: a new strategy is required.
27 Jan 2008
See a longer list of these articles.
Technical information about 'Lipoproteins'
Definition: Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. The large lipoproteins (CHYLOMICRONS; VLDL) are to transport triglycerides, and the small lipoproteins (LDL; HDL) are to transport cholesterol.
Registry Number: 0
Descriptor UI: D008074
Alternative terms: Lipoproteins; Circulating Lipoproteins; Lipoproteins, Circulating; Lipoprotein;
Related Mesh Headings: Apolipoproteins; Hyperlipoproteinemias; Hypolipoproteinemias; Lipoid Proteinosis of Urbach and Wiethe; Proteolipids; Receptors, Lipoprotein;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D10.532; D12.776.521;
Technical Notes: general or unspecified; prefer specifics; /blood: consider also HYPERLIPOPROTEINEMIA; /defic: consider also HYPOLIPOPROTEINEMIAS & specifics