Lipoproteins, LDL
Research News and Information

Sunday, November 22, 2009

Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling.

29 Nov 2009 The role of OxLDL in the generation and progression of atherosclerosis is well admitted. In addition, it is well known that atherosclerosis is often accompanied by perturbations in bone remodeling, resulting in osteoporosis. In the current studies, ... Read more...

Biomarkers of oxidative stress in heart failure.

29 Sep 2009 Oxidative stress is the relative excess of reactive oxygen species (ROS) versus endogenous defense mechanisms. Abundant evidence has demonstrated the role of ROS, along with reactive nitrogen species (RNS), in the pathophysiology of cardiovascular ... Read more...

In vivo extravasated human monocytes have an altered expression of CD16, HLA-DR, CD86, CD36 and CX(3)CR1.

29 Sep 2009 The phenotypic alterations in monocytes induced by extravasation in vivo are still largely unknown. We addressed the question whether a general phenotype of extravasated monocytes exists and whether this phenotype differs between healthy individuals ... Read more...

Latest indexed articles for 'Lipoproteins, LDL'

These are the very latest articles for this heading:

• Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. 29 Nov 2009
• Biomarkers of oxidative stress in heart failure. 29 Sep 2009
• Relation between low-density lipoprotein particle size and insulin and diabetes mellitus. 29 Sep 2009
• In vivo extravasated human monocytes have an altered expression of CD16, HLA-DR, CD86, CD36 and CX(3)CR1. 29 Sep 2009
• Newer antiphospholipid antibodies predict adverse outcomes in patients with acute coronary syndrome. 29 Sep 2009
• Tumor necrosis factor-alpha does not mediate diabetes-induced vascular inflammation in mice. 29 Sep 2009
• Estrogen decreases atherosclerosis in part by reducing hepatic acyl-CoA:cholesterol acyltransferase 2 (ACAT2) in monkeys. 29 Sep 2009
• Optimal medical therapy with or without percutaneous coronary intervention in older patients with stable coronary disease: a pre-specified subset analysis of the COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive druG Evaluation) trial. 27 Sep 2009
• A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. 22 Sep 2009
• Genetic association study of selected candidate genes (ApoB, LPL, Leptin) and telomere length in obese and hypertensive individuals. 20 Sep 2009
• Increased low density lipoprotein and increased likelihood of positive prostate biopsy in black americans. 14 Sep 2009
• Haptoglobin binds the antiatherogenic protein apolipoprotein E - impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes. 14 Sep 2009
• Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1. 5 Sep 2009
• Low-density lipoprotein in the setting of congestive heart failure: is lower really better? 30 Aug 2009
• Humoral mechanisms of atherogenesis. 30 Aug 2009
• Natural antibodies against phosphorylcholine in cardiovascular disease. 30 Aug 2009
• The IgM response to modified LDL in experimental atherosclerosis: hypochlorite-modified LDL IgM antibodies versus classical natural T15 IgM antibodies. 30 Aug 2009
• Vaccines modulating lipoprotein autoimmunity as a possible future therapy for cardiovascular disease. 30 Aug 2009
• Crude extracts of Solanum lyratum protect endothelial cells against oxidized low-density lipoprotein-induced injury by direct antioxidant action. 20 Aug 2009
• Macrophage diversity and polarization in atherosclerosis: a question of balance. 18 Aug 2009

See a longer list of these articles.

Technical information about 'Lipoproteins, LDL'

Definition: A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.

Registry Number: 0

Descriptor UI: D008077

Alternative terms: Lipoproteins, LDL; LDL Lipoproteins; Low-Density Lipoproteins; Lipoproteins, Low-Density; Low Density Lipoproteins; beta-Lipoproteins; beta Lipoproteins; LDL-1; LDL1; Low-Density Lipoprotein 1; Low Density Lipoprotein 1; LDL(1); LDL-2; LDL2; Low-Density Lipoprotein 2; Low Density Lipoprotein 2; LDL(2);

Related Mesh Headings: Receptors, LDL;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D10.532.515; D12.776.521.550;

History Note: 74(72)

Technical Notes: /defic: consider also HYPOBETALIPOPROTEINEMIAS