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Liver - Metabolism
Research News and Information

Saturday, November 21, 2009

Possible mechanisms involved in the discrepancy of hepatic and aortic endothelial nitric oxide synthases during the development of cirrhosis in rats.

25 Nov 2009 BACKGROUND/AIM: In cirrhosis, systemic nitric oxide (NO) overproduction and hepatic NO hypoproduction lead to arterial vasodilatation and portal hypertension. The mechanisms involved in these alterations in endothelial NO synthase (eNOS)-derived NO ... Read more...


The reduction of cell death and proliferation by p27(Kip1) minimizes DNA damage in an experimental model of genotoxicity.

13 Nov 2009 Hepatocellular carcinoma (HCC) is the fifth most commonly occurring cancer worldwide. The expression of p27 has been related to reduced severity of tumor grade and recurrence of HCC. The study assessed the role of p27 on the cell proliferation and ... Read more...


Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases.

30 Oct 2009 The nuclear factor-kappaB (NF-kappaB) signalling pathway regulates immune responses and is implicated in the pathogenesis of many inflammatory diseases. Given the well established pro-inflammatory functions of NF-kappaB, inhibition of this pathway ... Read more...

 

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Technical information about 'Liver'

Descriptor UI: D008099

Alternative terms: Liver; Livers;

Related Mesh Headings: Hepatectomy;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A03.620;

History Note: /cytology was LIVER CYTOLOGY 1964-65; /enzymology was LIVER ENZYMOLOGY 1964-65; /physiology was LIVER FUNCTION 1964-65

Technical Notes: /blood supply: consider also LIVER CIRCULATION; /cytol: consider also KUPFFER CELLS; /surg: consider also HEPATECTOMY & LIVER TRANSPLANTATION; inflammation = HEPATITIS & its specifics; specialty is HEPATOLOGY see GASTROENTEROLOGY; be careful: do not confuse "hepatic" with "intrahepatic": "intrahepatic" may refer to BILE DUCTS, INTRAHEPATIC & its dis, not LIVER

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