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Liver Cirrhosis - Blood
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Definition of 'Liver Cirrhosis'

Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Common names: Liver Cirrhosis; Hepatic Cirrhosis; Cirrhoses, Hepatic; Cirrhosis, Hepatic; Hepatic Cirrhoses; Cirrhosis, Liver; Cirrhoses, Liver; Liver Cirrhoses; Fibrosis, Liver; Fibroses, Liver; Liver Fibroses; Liver Fibrosis

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Monday, November 23, 2009

Targeting liver fibrosis: strategies for development and validation of antifibrotic therapies.

29 Sep 2009 We have made striking progress in our understanding of the biochemistry and cell biology that underlies liver fibrosis and cirrhosis, including the development of strategies and agents to prevent and reverse fibrosis. However, translation of this ... Read more...


Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6.

29 Sep 2009 More than 750 million people are at risk of infection with foodborne liver flukes. Opisthorchis viverrini is considered among the most important of these parasites, due to its strong association with cholangiocarcinoma (CCA). O. viverrini infection ... Read more...


Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.

12 Sep 2009 Ang-(1-7) (angiotensin-1-7), a peptide product of the recently described ACE (angiotensin-converting enzyme) homologue ACE2, opposes the harmful actions of AngII (angiotensin II) in cardiovascular tissues, but its role in liver disease is unknown. ... Read more...

 

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Technical information about 'Liver Cirrhosis'

Definition: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Descriptor UI: D008103

Alternative terms: Liver Cirrhosis; Hepatic Cirrhosis; Cirrhoses, Hepatic; Cirrhosis, Hepatic; Hepatic Cirrhoses; Cirrhosis, Liver; Cirrhoses, Liver; Liver Cirrhoses; Fibrosis, Liver; Fibroses, Liver; Liver Fibroses; Liver Fibrosis;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C06.552.630;

Online Note: use LIVER CIRRHOSIS to search LIVER CIRRHOSIS, POSTNECROTIC 1966-77

History Note: LIVER CIRRHOSIS, POSTNECROTIC was heading 1963-77

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