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Locomotion - Genetics
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Definition of 'Locomotion'

Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.

Common names: Locomotion; Locomotions

More technical Information...

Saturday, November 21, 2009

Optogenetic dissection of a behavioural module in the vertebrate spinal cord.

15 Sep 2009 Locomotion relies on neural networks called central pattern generators (CPGs) that generate periodic motor commands for rhythmic movements. In vertebrates, the excitatory synaptic drive for inducing the spinal CPG can originate from either ... Read more...


Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord.

14 Sep 2009 Hb9 interneurons (Hb9 INs) are putative components of the mouse spinal locomotor central pattern generator (CPG) and candidates for the rhythm-generating kernel. Studies in slices and hemisected spinal cords showed that Hb9 INs display TTX-resistant ... Read more...


Striatal expression of a calmodulin fragment improved motor function, weight loss, and neuropathology in the R6/2 mouse model of Huntington's disease.

14 Sep 2009 Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder, caused by a polyglutamine expansion in the huntingtin protein (htt). Increasing evidence suggests that transglutaminase (TGase) plays a critical role in the ... Read more...

 

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Technical information about 'Locomotion'

Definition: Movement or the ability to move from one place or another. It can refer to humans, vertebrate or invertebrate animals, and microorganisms.

Descriptor UI: D008124

Alternative terms: Locomotion; Locomotions;

Related Mesh Headings: Gait;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G07.700.560.500; G11.427.590.530.568;

Technical Notes: differentiate LOCOMOTION (getting from one point to another) from GAIT (how a man or major animal gets there), MOVEMENT (without necessarily locomoting), MOTOR ACTIVITY (movement assoc with behavior), WALKING (purposeful locomotion to get somewhere or for recreation, fitness or competition); CELL LOCOMOTION see CELL MOVEMENT is available

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