Locus Coeruleus
Research News and Information

Saturday, March 20, 2010

Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents.

30 Oct 2009 BACKGROUND: One underexploited property of anesthetics is their ability to probe neuronal regulation of arousal. At appropriate doses, anesthetics reversibly obtund conscious perception. However, individual anesthetic agents may accomplish this by ... Read more...

Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome.

28 Sep 2009 Rett syndrome (RTT) is a neurodevelopmental disorder caused by loss-of-function mutations in the Methyl-CpG-binding protein-2 (MECP2) gene and is characterized by derangements in cognition, behavior, motor control, respiration and autonomic ... Read more...

Dendritic synthesis and release of the neuropeptide galanin: morphological evidence from studies on rat locus coeruleus neurons.

18 Sep 2009 Dendritic synthesis and release of neuropeptides have been demonstrated in hypothalamic neurosecretory neurons. Here we tested whether this mechanism may be applicable to galanin in rat locus coeruleus (LC) neurons. Light and electron microscopic ... Read more...

Latest indexed articles for 'Locus Coeruleus'

These are the very latest articles for this heading:

• Halothane-induced hypnosis is not accompanied by inactivation of orexinergic output in rodents. 30 Oct 2009
• Pathophysiology of locus ceruleus neurons in a mouse model of Rett syndrome. 28 Sep 2009
• Dendritic synthesis and release of the neuropeptide galanin: morphological evidence from studies on rat locus coeruleus neurons. 18 Sep 2009
• Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice. 17 Aug 2009
• Gene expression analyses of neurons, astrocytes, and oligodendrocytes isolated by laser capture microdissection from human brain: detrimental effects of laboratory humidity. 13 Aug 2009
• Marked behavioral activation from inhibitory stimulation of locus coeruleus alpha1-adrenoceptors by a full agonist. 22 Jul 2009
• Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice. 21 Jul 2009
• Glucocorticoid status affects antidepressant regulation of locus coeruleus tyrosine hydroxylase and dorsal raphé tryptophan hydroxylase gene expression. Jul 2009
• Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. 29 Jun 2009
• Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. 29 Jun 2009
• Developmental emergence of power-law wake behavior depends upon the functional integrity of the locus coeruleus. 29 Jun 2009
• Beneficial effects of antioxidant-enriched diet for tyrosine hydroxylase-positive neurons in ventral mesencephalic tissue in oculo grafts. 29 Jun 2009
• Chemosensory responses to CO2 in multiple brain stem nuclei determined using a voltage-sensitive dye in brain slices from rats. 22 Jun 2009
• Effects of estrogen receptor alpha and beta gene deletion on estrogenic induction of progesterone receptors in the locus coeruleus in female mice. 22 Jun 2009
• Unilateral rest tremor in vascular parkinsonism associated with a contralateral lesion of the locus coeruleus. 13 Jun 2009
• In vivo mapping of the human locus coeruleus. 9 Jun 2009
• Protein kinase A-dependence of the supraspinally mediated analgesic effects of gabapentin on thermal and mechanical hypersensitivity. 3 Jun 2009
• Prolactin-releasing peptide regulates the cardiovascular system via corticotrophin-releasing hormone. 30 May 2009
• Collateral projection from the locus coeruleus to whisker-related sensory and motor brain regions of the rat. 30 May 2009
• Extracellular norepinephrine, norepinephrine receptor and transporter protein and mRNA levels are differentially altered in the developing rat brain due to dietary iron deficiency and manganese exposure. 26 May 2009

See a longer list of these articles.

Technical information about 'Locus Coeruleus'

Definition: Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis.

Descriptor UI: D008125

Alternative terms: Locus Coeruleus; Locus Ceruleus; Nucleus Pigmentosus Pontis; Pontis, Nucleus Pigmentosus; Locus Caeruleus;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.132.659.473; A08.186.211.132.810.428.600.500; A08.186.211.653.473; A08.186.211.865.428.600.500;

History Note: 78