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Long-Term Potentiation - Physiology
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Definition of 'Long-Term Potentiation'

A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long-term potentiation suggest that it may be a cellular mechanism of learning and memory.

Common names: Long-Term Potentiation; Long Term Potentiation; Long-Term Potentiations; Potentiation, Long-Term; Potentiations, Long-Term

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Saturday, November 21, 2009

Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop.

27 Oct 2009 Theta oscillations are believed to play an important role in the coordination of neuronal firing in the entorhinal (EC)-hippocampal system but the underlying mechanisms are not known. We simultaneously recorded from neurons in multiple regions of ... Read more...


Metaplasticity governs natural experience-driven plasticity of nascent embryonic brain circuits.

27 Oct 2009 During embryogenesis, brain neurons receiving the same sensory input may undergo potentiation or depression. While the origin of variable plasticity in vivo is unknown, it plays a key role in shaping dynamic neural circuit refinement. Here, we ... Read more...


Interfering with the actin network and its effect on long-term potentiation and synaptic tagging in hippocampal CA1 neurons in slices in vitro.

28 Sep 2009 Long-term potentiation (LTP) is a cellular correlate for memory formation, which requires the dynamic changes of the actin cytoskeleton. As shown by others, the polymerization of the actin network is important for early stages of LTP. Here, we ... Read more...

 

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Technical information about 'Long-Term Potentiation'

Definition: A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long-term potentiation suggest that it may be a cellular mechanism of learning and memory.

Descriptor UI: D017774

Alternative terms: Long-Term Potentiation; Long Term Potentiation; Long-Term Potentiations; Potentiation, Long-Term; Potentiations, Long-Term;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G11.561.600.635.350;

History Note: 94

Technical Notes: note category: "a persistent increase in synaptic efficacy"; DF: LTP

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