Long-Term Potentiation
Research News and Information

Saturday, November 21, 2009

Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability.

2 Nov 2009 The effects of lifelong, moderate excess release of glutamate (Glu) in the CNS have not been previously characterized. We created a transgenic (Tg) mouse model of lifelong excess synaptic Glu release in the CNS by introducing the gene for glutamate ... Read more...

Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade.

30 Oct 2009 BACKGROUND: The memory-blocking properties of general anesthetics have recently received considerable attention because of concerns related to intraoperative awareness and postoperative cognitive dysfunction. The goal of this study was to identify ... Read more...

Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop.

27 Oct 2009 Theta oscillations are believed to play an important role in the coordination of neuronal firing in the entorhinal (EC)-hippocampal system but the underlying mechanisms are not known. We simultaneously recorded from neurons in multiple regions of ... Read more...

Latest indexed articles for 'Long-Term Potentiation'

These are the very latest articles for this heading:

• Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. 2 Nov 2009
• Etomidate targets alpha5 gamma-aminobutyric acid subtype A receptors to regulate synaptic plasticity and memory blockade. 30 Oct 2009
• Theta oscillations provide temporal windows for local circuit computation in the entorhinal-hippocampal loop. 27 Oct 2009
• Metaplasticity governs natural experience-driven plasticity of nascent embryonic brain circuits. 27 Oct 2009
• Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. 12 Oct 2009
• Cocaine exposure in utero alters synaptic plasticity in the medial prefrontal cortex of postnatal rats. 5 Oct 2009
• Long-term potentiation: two pathways meet at neurogranin. 5 Oct 2009
• Interfering with the actin network and its effect on long-term potentiation and synaptic tagging in hippocampal CA1 neurons in slices in vitro. 28 Sep 2009
• LTD induction suppresses LTP-induced hippocampal adult neurogenesis. 21 Sep 2009
• NMDA receptor phosphorylation at a site affected in schizophrenia controls synaptic and behavioral plasticity. 21 Sep 2009
• The role of granulocyte-colony stimulating factor (G-CSF) in the healthy brain: a characterization of G-CSF-deficient mice. 14 Sep 2009
• Dopamine enables in vivo synaptic plasticity associated with the addictive drug nicotine. 8 Sep 2009
• NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory. 8 Sep 2009
• Nicotine's Allure. 8 Sep 2009
• Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome. 7 Sep 2009
• Short trains of theta frequency stimulation enhance CA1 pyramidal neuron excitability in the absence of synaptic potentiation. 7 Sep 2009
• Non-Hebbian synaptic plasticity induced by repetitive postsynaptic action potentials. 7 Sep 2009
• Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. 4 Sep 2009
• Short-term synaptic plasticity in the nociceptive thalamic-anterior cingulate pathway. 2 Sep 2009
• Reelin signaling antagonizes beta-amyloid at the synapse. 31 Aug 2009

See a longer list of these articles.

Technical information about 'Long-Term Potentiation'

Definition: A persistent increase in synaptic efficacy, usually induced by appropriate activation of the same synapses. The phenomenological properties of long-term potentiation suggest that it may be a cellular mechanism of learning and memory.

Descriptor UI: D017774

Alternative terms: Long-Term Potentiation; Long Term Potentiation; Long-Term Potentiations; Potentiation, Long-Term; Potentiations, Long-Term;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G11.561.600.635.350;

History Note: 94

Technical Notes: note category: "a persistent increase in synaptic efficacy"; DF: LTP