Lupus Erythematosus, Systemic - Diagnosis
Research News and Information

Saturday, November 21, 2009

Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus.

13 Sep 2009 OBJECTIVE: Selection of flare as the primary outcome variable in systemic lupus erythematosus (SLE) clinical trials fails to capture patients with persistently active disease (PAD). We sought to elucidate the frequency and determinants of flare and ... Read more...

The impact of flare on disease costs of patients with systemic lupus erythematosus.

13 Sep 2009 OBJECTIVE: To evaluate both direct and indirect costs of systemic lupus erythematosus (SLE) patients with and without flares from a societal perspective, and to investigate the impact of the severity and clinical manifestations of flares on ... Read more...

Antiphospholipid syndrome and systemic lupus erythematosus: are they separate entities or just clinical presentations on the same scale?

30 Aug 2009 PURPOSE OF REVIEW: Although originally described in the context of systemic lupus erythematosus, antiphospholipid syndrome was then recognized as a primary antiphospholipid syndrome without any underlying autoimmune disease in almost half of the ... Read more...

Latest indexed articles for 'Lupus Erythematosus, Systemic - Diagnosis'

These are the very latest articles for this heading:

• Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus. 13 Sep 2009
• The impact of flare on disease costs of patients with systemic lupus erythematosus. 13 Sep 2009
• A 65-year-old man with longstanding seropositive rheumatoid arthritis and lower extremity ulceration. 13 Sep 2009
• Antiphospholipid syndrome and systemic lupus erythematosus: are they separate entities or just clinical presentations on the same scale? 30 Aug 2009
• Relevance of anti-C1q autoantibodies to lupus nephritis. 30 Aug 2009
• Anti-C1q antibodies in juvenile-onset systemic lupus erythematosus. 30 Aug 2009
• Autoimmune thyroid disease and autoimmune rheumatic disorders: a two-sided analysis. 30 Aug 2009
• High sensitive detection of double-stranded DNA autoantibodies by a modified Crithidia luciliae immunofluorescence test. 30 Aug 2009
• Acute abdomen: always a puzzle (Case presentation). 30 Aug 2009
• Regression of systemic lupus erythematosus after development of an acquired toll-like receptor signaling defect and antibody deficiency. 30 Aug 2009
• Neutrophil gelatinase-associated lipocalin is a predictor of the course of global and renal childhood-onset systemic lupus erythematosus disease activity. 30 Aug 2009
• Networking in Europe for special centres of excellence for autoimmune diseases. 30 Aug 2009
• Acute inflammatory demyelinating polyneuropathy as the initial presentation of lupus. 30 Aug 2009
• Devic's syndrome as initial presentation of systemic lupus erythematosus. 30 Aug 2009
• Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells. 10 Aug 2009
• Systemic lupus erythematosus and C1q: A quantitative ELISA for determining C1q levels in serum. 30 Jul 2009
• Putting a face on systemic lupus erythematosus. 30 Jul 2009
• The case of SLE associated Sneddon-Wilkinson pustular disease successfully and safely treated with infliximab. 30 Jul 2009
• Survival analysis and prognostic indicators of systemic lupus erythematosus in Pakistani patients. 30 Jul 2009
• The variable clinical picture of drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms in relation to the eliciting drug. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Lupus Erythematosus, Systemic'

Definition: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Descriptor UI: D008180

Alternative terms: Lupus Erythematosus, Systemic; Systemic Lupus Erythematosus; Lupus Erythematosus Disseminatus; Libman-Sacks Disease; Disease, Libman-Sacks; Libman Sacks Disease;

Related Mesh Headings: Lupus Coagulation Inhibitor; Antiphospholipid Syndrome; Vasculitis, Central Nervous System;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C17.300.480; C20.111.590;

Technical Notes: if not specified as "systemic" it is still probably correct to index here, not also discoid; LUPUS NEPHRITIS is also available; LE CELLS see NEUTROPHILS is also available: use LUPUS ERYTHEMATOSUS, SYSTEMIC /blood or /pathol + NEUTROPHILS for discussion of the LE cells as cells; DF: SLE