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Lupus Erythematosus, Systemic - Physiopathology
Research News and Information
Definition of 'Lupus Erythematosus, Systemic'A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. |
Sunday, November 22, 2009
25-hydroxyvitamin D and cardiovascular risk factors in women with systemic lupus erythematosus.
13 Oct 2009
OBJECTIVE: Low serum levels of 25-hydroxyvitamin D (25[OH]D; vitamin D) are associated with a higher frequency of cardiovascular disease and risk factors in the general population. Vitamin D deficiency has also been noted in systemic lupus ... Read more...
13 Sep 2009
OBJECTIVE: To determine the factors associated with increased levels of fatigue over the course of the disease in systemic lupus erythematosus (SLE) patients from LUpus in MInorities: NAture versus nurture, a longitudinal multiethnic cohort. ... Read more...
Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus.
13 Sep 2009
OBJECTIVE: Selection of flare as the primary outcome variable in systemic lupus erythematosus (SLE) clinical trials fails to capture patients with persistently active disease (PAD). We sought to elucidate the frequency and determinants of flare and ... Read more...
Latest indexed articles for 'Lupus Erythematosus, Systemic - Physiopathology'
These are the very latest articles for this heading:
- 25-hydroxyvitamin D and cardiovascular risk factors in women with systemic lupus erythematosus.
13 Oct 2009 - Disease activity and damage are not associated with increased levels of fatigue in systemic lupus erythematosus patients from a multiethnic cohort: LXVII.
13 Sep 2009 - Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus.
13 Sep 2009 - The impact of flare on disease costs of patients with systemic lupus erythematosus.
13 Sep 2009 - Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome.
30 Aug 2009 - CXCR3, inflammation, and autoimmune diseases.
30 Aug 2009 - Regression of systemic lupus erythematosus after development of an acquired toll-like receptor signaling defect and antibody deficiency.
30 Aug 2009 - Shared symptoms in rheumatic diseases: a blessing or a curse?
30 Aug 2009 - Putting a face on systemic lupus erythematosus.
30 Jul 2009 - Atherosclerosis in autoimmune rheumatic diseases-mechanisms and clinical findings.
30 Jul 2009 - Adipocytokines in systemic lupus erythematosus: relationship to inflammation, insulin resistance and coronary atherosclerosis.
30 Jul 2009 - The variable clinical picture of drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms in relation to the eliciting drug.
30 Jul 2009 - Respiratory manifestations of systemic lupus erythematosus: old and new concepts.
30 Jul 2009 - Studies of cell-mediated immune responses to influenza vaccination in systemic lupus erythematosus.
30 Jul 2009 - The role of neutrophil apoptosis in juvenile-onset systemic lupus erythematosus.
30 Jul 2009 - The peroxisome proliferator-activated receptor gamma agonist pioglitazone improves cardiometabolic risk and renal inflammation in murine lupus.
18 Jul 2009 - Bone health in systemic lupus erythematosus.
29 Jun 2009 - B lymphocyte cytokines and rheumatic autoimmune disease.
29 Jun 2009 - Systemic lupus erythematosus and ulcerative colitis.
29 Jun 2009 - Clinical manifestations and outcomes of antithrombotic treatment of the Tan Tock Seng Hospital Singapore antiphospholipid syndrome cohort.
29 Jun 2009
See a longer list of these articles.
Technical information about 'Lupus Erythematosus, Systemic'
Definition: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Descriptor UI: D008180
Alternative terms: Lupus Erythematosus, Systemic; Systemic Lupus Erythematosus; Lupus Erythematosus Disseminatus; Libman-Sacks Disease; Disease, Libman-Sacks; Libman Sacks Disease;
Related Mesh Headings: Lupus Coagulation Inhibitor; Antiphospholipid Syndrome; Vasculitis, Central Nervous System;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C17.300.480; C20.111.590;
Technical Notes: if not specified as "systemic" it is still probably correct to index here, not also discoid; LUPUS NEPHRITIS is also available; LE CELLS see NEUTROPHILS is also available: use LUPUS ERYTHEMATOSUS, SYSTEMIC /blood or /pathol + NEUTROPHILS for discussion of the LE cells as cells; DF: SLE