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Lysosomal-Associated Membrane Protein 1 - Metabolism
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Definition of 'Lysosomal-Associated Membrane Protein 1'

An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ENDOSOMES; and the PLASMA MEMBRANE. In PLATELETS and T-LYMPHOCYTES it may play a role in the cellular degranulation process.

Common names: Lysosomal-Associated Membrane Protein 1; Lysosomal Associated Membrane Protein 1; CD107a Antigen; LGP120 Protein; LAMP1 Protein; LAMPA Protein; Antigens, CD107a; CD107a Antigens

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Sunday, November 22, 2009

Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells.

25 Aug 2009 BACKGROUND: Umbilical cord blood (UCB) is enriched with transplantable CD34+ cells. In addition to CD34-expressing haematopoietic stem cells (HSC), human UCB contains a rare population of CD34-lineage- cells endowed with the ability to differentiate ... Read more...


Adherent-invasive Escherichia coli, strain LF82 disrupts apical junctional complexes in polarized epithelia.

24 Aug 2009 BACKGROUND: Although bacteria are implicated in the pathogenesis of chronic inflammatory bowel diseases (IBD), mechanisms of intestinal injury and immune activation remain unclear. Identification of adherent-invasive Escherichia coli (AIEC) strains ... Read more...


The clavesin family, neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology.

Aug 2009 Clathrin-coated vesicles (CCVs) originating from the trans-Golgi network (TGN) provide a major transport pathway from the secretory system to endosomes/lysosomes. Herein we describe paralogous Sec14 domain-bearing proteins, clavesin 1/CRALBPL and ... Read more...

 

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Technical information about 'Lysosomal-Associated Membrane Protein 1'

Definition: An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ENDOSOMES; and the PLASMA MEMBRANE. In PLATELETS and T-LYMPHOCYTES it may play a role in the cellular degranulation process.

Registry Number: 0

Descriptor UI: D052118

Alternative terms: Lysosomal-Associated Membrane Protein 1; Lysosomal Associated Membrane Protein 1; CD107a Antigen; LGP120 Protein; LAMP1 Protein; LAMPA Protein; Antigens, CD107a; CD107a Antigens;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.395.550.550.500; D12.776.395.550.625.449; D12.776.543.550.527.500; D12.776.543.550.625.449; D12.776.543.750.705.675.554; D23.050.301.264.035.512; D23.101.100.110.512;

History Note: 2006(1986)

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