Lysosomal-Associated Membrane Protein 1
Research News and Information

Sunday, November 22, 2009

CD3 expression distinguishes two gammadeltaT cell receptor subsets with different phenotype and effector function in tuberculous pleurisy.

30 Aug 2009 Tuberculous pleurisy is a naturally occurring site of Mycobacterium tuberculosis (Mtb) infection. Herein, we describe the expression of activation, natural killer (NK) and cell migration markers, as well as effector functions from gammadeltaT cells ... Read more...

Education of hyporesponsive NK cells by cytokines.

30 Aug 2009 NK-cell tolerance to self is mediated via engagement of inhibitory receptors by cognate MHC molecules. This event is critical for NK-cell education to achieve functional competence. Thus, NK cells expressing self-MHC-specific inhibitory receptors ... Read more...

Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells.

25 Aug 2009 BACKGROUND: Umbilical cord blood (UCB) is enriched with transplantable CD34+ cells. In addition to CD34-expressing haematopoietic stem cells (HSC), human UCB contains a rare population of CD34-lineage- cells endowed with the ability to differentiate ... Read more...

Latest indexed articles for 'Lysosomal-Associated Membrane Protein 1'

These are the very latest articles for this heading:

• CD3 expression distinguishes two gammadeltaT cell receptor subsets with different phenotype and effector function in tuberculous pleurisy. 30 Aug 2009
• Education of hyporesponsive NK cells by cytokines. 30 Aug 2009
• Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells. 25 Aug 2009
• Adherent-invasive Escherichia coli, strain LF82 disrupts apical junctional complexes in polarized epithelia. 24 Aug 2009
• The clavesin family, neuron-specific lipid- and clathrin-binding Sec14 proteins regulating lysosomal morphology. Aug 2009
• In vitro tests in drug hypersensitivity diagnosis. 30 Jul 2009
• Elevated natural killer cell activity despite altered functional and phenotypic profile in Ugandans with HIV-1 clade A or clade D infection. 30 Jul 2009
• Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses. 22 Jun 2009
• Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors. 30 May 2009
• Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections. 22 May 2009
• Differential effects of EGFR ligands on endocytic sorting of the receptor. 17 May 2009
• A programmed switch from IL-15- to IL-2-dependent activation in human NK cells. 13 May 2009
• Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism. 11 May 2009
• Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients. 3 May 2009
• A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1. 14 Apr 2009
• Early endosomes and endosomal coatomer are required for autophagy. 11 Apr 2009
• Intracellular transport of human immunodeficiency virus type 1 genomic RNA and viral production are dependent on dynein motor function and late endosome positioning. 11 Mar 2009
• Retention of viability, cytotoxicity, and response to IL-2, IL-15, or IFN-alpha by human NK cells after CD107a degranulation. 21 Feb 2009
• Tumor progression inhibits the induction of multifunctionality in adoptively transferred tumor-specific CD8+ T cells. 30 Dec 2008
• Comprehensive analysis of NK cell function in whole blood samples. Dec 2008

See a longer list of these articles.

Technical information about 'Lysosomal-Associated Membrane Protein 1'

Definition: An abundant lysosomal-associated membrane protein that has been found to shuttle between LYSOSOMES; ENDOSOMES; and the PLASMA MEMBRANE. In PLATELETS and T-LYMPHOCYTES it may play a role in the cellular degranulation process.

Registry Number: 0

Descriptor UI: D052118

Alternative terms: Lysosomal-Associated Membrane Protein 1; Lysosomal Associated Membrane Protein 1; CD107a Antigen; LGP120 Protein; LAMP1 Protein; LAMPA Protein; Antigens, CD107a; CD107a Antigens;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.395.550.550.500; D12.776.395.550.625.449; D12.776.543.550.527.500; D12.776.543.550.625.449; D12.776.543.750.705.675.554; D23.050.301.264.035.512; D23.101.100.110.512;

History Note: 2006(1986)