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Malate Dehydrogenase
Research News and Information
Definition of 'Malate Dehydrogenase'An enzyme that catalyzes the conversion of (S)-malate and NAD+ to oxaloacetate and NADH. EC 1.1.1.37. Common names: Malate Dehydrogenase; Dehydrogenase, Malate; NAD-Malate Dehydrogenase; Dehydrogenase, NAD-Malate; NAD Malate Dehydrogenase; Malic Dehydrogenase; Dehydrogenase, Malic |
Tuesday, March 16, 2010
8 Sep 2009 
Human G93A-superoxide dismutase-1 (G93AhSOD1) mutation causes amyotrophic lateral sclerosis (ALS) in rodents and humans. Recent observations indicate gain of interaction of G93AhSOD1 with cytosolic malate dehydrogenase (MDH1) and subsequent ... Read more...
31 Aug 2009 The Arabidopsis thaliana genome contains four genes encoding NADP-malic enzymes (NADP-ME1-4). Two isoenzymes, NADP-ME2 and NADP-ME3, which are shown to be located in the cytosol, share a remarkably high degree of identity (90%). However, they ... Read more...
13 Aug 2009 Despite interest in malic enzyme(ME)s in insulin cells, mitochondrial malic enzyme (ME2) has only been studied with estimates of mRNA or with mRNA knockdown. Because an mRNA's level does not necessarily reflect the level of its cognate enzyme, we ... Read more...
Latest indexed articles for 'Malate Dehydrogenase'
These are the very latest articles for this heading:
- A novel decoy that interrupts G93A-superoxide dismutase gain of interaction with malate dehydrogenase improves survival in an amyotrophic lateral sclerosis cell model. 8 Sep 2009
- Identification of domains involved in the allosteric regulation of cytosolic Arabidopsis thaliana NADP-malic enzymes. 31 Aug 2009
- Mitochondrial malic enzyme (ME2) in pancreatic islets of the human, rat and mouse and clonal insulinoma cells. 13 Aug 2009
- Features of structural organization and expression regulation of malate dehydrogenase isoforms from Rhodobacter sphaeroides strain 2R. 29 Jun 2009
- The response difference of mitochondria in recalcitrant Antiaris toxicaria axes and orthodox Zea mays embryos to dehydration injury. 29 Jun 2009
- Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. 25 Jun 2009
- Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix. 21 Jun 2009
- Comparative genomic analysis of C4 photosynthetic pathway evolution in grasses. 21 Jun 2009
- Production of enzyme reactors after separation by non-denaturing two-dimensional electrophoresis and immobilization on membrane. 9 Jun 2009
- Identifying sleep regulatory genes using a Drosophila model of insomnia. Jun 2009
- Potential application of the recombinant Escherichia coli-synthesized heme as a bioavailable iron source.
30 May 2009 - Establishment of a continuous culture system for Entamoeba muris and analysis of the small subunit rRNA gene. 30 May 2009
- Long-range interaction between the enzyme active site and a distant allosteric site in the human mitochondrial NAD(P)+-dependent malic enzyme. 20 May 2009
- Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons. 16 May 2009
- Dual roles of Lys(57) at the dimer interface of human mitochondrial NAD(P)+-dependent malic enzyme. 11 May 2009
- Establishment and characterization of a fibroblast line from Simmental cattle. 4 May 2009
- Cloning, identification, expression analysis and phylogenetic relevance of two NADP-dependent malic enzyme genes from hexaploid wheat. 4 May 2009
- Functional roles of the tetramer organization of malic enzyme. 3 May 2009
- [Structural-functional transformation of the malate dehydrogenase system of the bacterium Sphaerotilus sp. strain D-507 depending on nutritional mode] 29 Apr 2009
- Effect of caponization and different exogenous androgen on hepatic lipid and beta-oxidase of male chickens. 29 Apr 2009
See a longer list of these articles.
Technical information about 'Malate Dehydrogenase'
Definition: An enzyme that catalyzes the conversion of (S)-malate and NAD+ to oxaloacetate and NADH. EC 1.1.1.37.
Chemical name: (S)-Malate:NAD+ oxidoreductase
Registry Number: EC 1.1.1.37
Descriptor UI: D008291
Alternative terms: Malate Dehydrogenase; Dehydrogenase, Malate; NAD-Malate Dehydrogenase; Dehydrogenase, NAD-Malate; NAD Malate Dehydrogenase; Malic Dehydrogenase; Dehydrogenase, Malic;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;
Tree Number: D08.811.682.047.605;
Online Note: use MALATE DEHYDROGENASE to search MALIC ENZYME 1983-93
History Note: MALIC ENZYME was see MALATE DEHYDROGENASE 1983-93