Mass Spectrometry
Research News and Information

Saturday, November 21, 2009

Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase.

15 Nov 2009 While covalent catalytic intermediates of retaining alpha-transglycosylases have been structurally characterized previously, no such information for a hydrolytic alpha-amylase has been obtained. This study presents a new "in situ" enzymatic ... Read more...

Synthesis and evaluation of a novel class of G-quadruplex-stabilizing small molecules based on the 1,3-phenylene-bis(piperazinyl benzimidazole) system.

15 Nov 2009 Achieving stabilization of telomeric DNA in G-quadruplex conformation by various organic compounds has been an important goal for the medicinal chemists seeking to develop new anticancer agents. Several compounds are known to stabilize ... Read more...

C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin.

30 Oct 2009 Reelin is a secreted glycoprotein that plays pivotal roles in the development and function of the brain, but how it activates downstream intracellular signaling is not fully understood. We have recently reported that the highly conserved C-terminal ... Read more...

Latest indexed articles for 'Mass Spectrometry'

These are the very latest articles for this heading:

• Directed "in situ" inhibitor elongation as a strategy to structurally characterize the covalent glycosyl-enzyme intermediate of human pancreatic alpha-amylase. 15 Nov 2009
• Synthesis and evaluation of a novel class of G-quadruplex-stabilizing small molecules based on the 1,3-phenylene-bis(piperazinyl benzimidazole) system. 15 Nov 2009
• C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin. 30 Oct 2009
• Cyclosporin A inhibits UV-radiation-induced membrane damage but is unable to inhibit carboxyatractyloside-induced permeability transition. 30 Oct 2009
• The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription. 30 Oct 2009
• Molds and mycotoxins in indoor environments--a survey in water-damaged buildings. 30 Oct 2009
• Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I. 18 Oct 2009
• The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. 18 Oct 2009
• Copper binding to beta-2-microglobulin and its pre-amyloid oligomers. 18 Oct 2009
• Structural insights into glucan phosphatase dynamics using amide hydrogen-deuterium exchange mass spectrometry. 18 Oct 2009
• Deep-sea archaea fix and share nitrogen in methane-consuming microbial consortia. 14 Oct 2009
• Microbiology. Fantastic fixers. 14 Oct 2009
• The isolation and identification of a secreted biomarker associated with cell stress in serum-free CHO cell culture. 13 Oct 2009
• Clinical assays for human chorionic gonadotropin: what should we measure and how? 29 Sep 2009
• Using X-ray microscopy and Hg L3 XANES to study Hg binding in the rhizosphere of Spartina cordgrass. 29 Sep 2009
• XANES evidence for oxidation of Cr(III) to Cr(VI) by Mn-oxides in a lateritic regolith developed on serpentinized ultramafic rocks of New Caledonia. 29 Sep 2009
• Detection of S(IV) species in aerosol particles using XANES spectroscopy. 29 Sep 2009
• Trace element concentration in wheat grain: results from the Swedish long-term soil fertility experiments and national monitoring program. 29 Sep 2009
• Use of liquid chromatography/tandem mass spectrometry and online databases for identification of phosphocholines and lysophosphatidylcholines in human red blood cells. 29 Sep 2009
• Determination of a trace level enol impurity by on-line hydrogen/deuterium exchange combined with ultra-high mass resolution and ultra-high mass accuracy Fourier transform ion cyclotron resonance mass spectrometry. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Mass Spectrometry'

Definition: An analytical method used in determining the identity of a chemical based on its mass using mass analyzers/mass spectrometers.

Descriptor UI: D013058

Alternative terms: Mass Spectrometry; Mass Spectroscopy; Spectrum Analysis, Mass; Analysis, Mass Spectrum; Analyses, Mass Spectrum; Mass Spectrum Analyses; Spectrum Analyses, Mass; Mass Spectrum Analysis; Spectrometry, Mass; Spectroscopy, Mass;

Allowable Qualifiers: classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; ethics;

Tree Number: E05.196.566;

History Note: 2007 (1971)