Matrix Metalloproteinase 2 - Metabolism
Research News and Information

Sunday, November 22, 2009

CXCL14 inhibits trophoblast outgrowth via a paracrine/autocrine manner during early pregnancy in mice.

30 Oct 2009 CXCL14, a member of chemokine family, was previously known to participate in many pathophysiological events, such as leukocytes recruitment and tumor suppression. However, it remained largely unknown whether CXCL14 is a physiological player during ... Read more...

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

3 Oct 2009 Platelet activation at a site of vascular injury is essential for the arrest of bleeding; however, excessive platelet activation at a site of arterial damage can result in the unwarranted formation of arterial thrombi, precipitating acute myocardial ... Read more...

Absence of thrombospondin-2 causes age-related dilated cardiomyopathy.

3 Oct 2009 BACKGROUND: The progressive shift from a young to an aged heart is characterized by alterations in the cardiac matrix. The present study investigated whether the matricellular protein thrombospondin-2 (TSP-2) may affect cardiac dimensions and ... Read more...

Latest indexed articles for 'Matrix Metalloproteinase 2 - Metabolism'

These are the very latest articles for this heading:

• CXCL14 inhibits trophoblast outgrowth via a paracrine/autocrine manner during early pregnancy in mice. 30 Oct 2009
• Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo. 3 Oct 2009
• Absence of thrombospondin-2 causes age-related dilated cardiomyopathy. 3 Oct 2009
• Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol. 29 Sep 2009
• Histological and molecular analysis of the biceps tendon long head post-tenotomy. 29 Sep 2009
• Constitutively active MEK1 is sufficient to induce epithelial-to-mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis. 29 Sep 2009
• Suppression of IkappaBalpha increases the expression of matrix metalloproteinase-2 in human ciliary muscle cells. 24 Sep 2009
• Understanding abdominal aortic aneurysm. 8 Sep 2009
• Effects of oral contraceptives or a gonadotropin-releasing hormone agonist on ovarian carcinogenesis in genetically engineered mice. 6 Sep 2009
• Expression of matrix metalloproteinases MMP-2, MMP-9 and their tissue inhibitors TIMP-1 and TIMP-2 in the epithelium and stroma of salivary gland pleomorphic adenomas. 30 Aug 2009
• Role of angiotensin II type 1 receptor in cerebral aneurysm formation in rats. 30 Aug 2009
• Enhanced invasiveness of drug-resistant acute myeloid leukemia cells through increased expression of matrix metalloproteinase-2. 30 Aug 2009
• Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. 25 Aug 2009
• S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4. 25 Aug 2009
• Matrix metalloproteinase-2 is elevated in midtrimester amniotic fluid prior to the development of preeclampsia. 21 Aug 2009
• In vitro differences between smooth muscle cells derived from varicose veins and normal veins. 20 Aug 2009
• Upregulation of matrix metalloproteinase-2 in the arterial vasculature contributes to stiffening and vasomotor dysfunction in patients with chronic kidney disease. 15 Aug 2009
• Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion. 12 Aug 2009
• Collagen I regulates matrix metalloproteinase-2 activation in osteosarcoma cells independent of S100A4. 11 Aug 2009
• Overcoming macrophage-mediated axonal dieback following CNS injury. 10 Aug 2009

See a longer list of these articles.

Technical information about 'Matrix Metalloproteinase 2'

Definition: A secreted endopeptidase homologous with INTERSTITIAL COLLAGENASE, but which possesses an additional fibronectin-like domain.

Registry Number: EC 3.4.24.24

Descriptor UI: D020778

Alternative terms: Matrix Metalloproteinase 2; Metalloproteinase 2, Matrix; MMP-2 Metalloproteinase; MMP 2 Metalloproteinase; Metalloproteinase, MMP-2; MMP2 Metalloproteinase; Metalloproteinase, MMP2; 72-kDa Type IV Collagenase; 72 kDa Type IV Collagenase; Gelatinase A; Matrix Metalloproteinase-2; 72-kDa Gelatinase; 72 kDa Gelatinase; Gelatinase, 72-kDa;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.277.656.300.480.205.352; D08.811.277.656.300.480.252.420; D08.811.277.656.300.480.525.700.150; D08.811.277.656.675.374.205.352; D08.811.277.656.675.374.252.420; D08.811.277.656.675.374.525.700.150;

History Note: 2007(2000)

Technical Notes: /antag is permitted but TISSUE INHIBITOR OF METALLOPROTEINASE-2 is available