Maze Learning - Drug effects
Research News and Information

Saturday, November 21, 2009

MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning.

29 Sep 2009 3,4-Methylenedioxymethamphetamine (MDMA) is a drug of abuse worldwide and a selective serotonin (5-HT) neurotoxin. An important factor in the risk of drug abuse and relapse is stress. Although multiple parallels exist between MDMA abuse and stress, ... Read more...

Double dissociation and hierarchical organization of strategy switches and reversals in the rat PFC.

29 Sep 2009 Prelimbic-infralimbic cortex (PL-IL) and orbitofrontal cortex (OFC) influence behavioral flexibility in the rat. The authors tested the effects of PL-IL or OFC infusion with the GABA agonist muscimol in the context of 2 flexible responding tasks: ... Read more...

Formation of spatial memory in rats with ischemic lesions to the prefrontal cortex; effects of a synthetic analog of ACTH(4-7).

21 Sep 2009 Photochemically induced thrombosis of blood vessels in the prefrontal cortex in rats was shown to lead to ischemic infarcts in the lesion zone. Bilateral ischemic lesioning of the prefrontal cortex degraded measures of spatial memory when animals ... Read more...

Latest indexed articles for 'Maze Learning - Drug effects'

These are the very latest articles for this heading:

• MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning. 29 Sep 2009
• Double dissociation and hierarchical organization of strategy switches and reversals in the rat PFC. 29 Sep 2009
• Formation of spatial memory in rats with ischemic lesions to the prefrontal cortex; effects of a synthetic analog of ACTH(4-7). 21 Sep 2009
• Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease. 17 Sep 2009
• NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory. 8 Sep 2009
• Hippocampal-dependent spatial memory functions might be lateralized in rats: An approach combining gene expression profiling and reversible inactivation. 30 Aug 2009
• Simvastatin therapy prevents brain trauma-induced increases in beta-amyloid peptide levels. 30 Aug 2009
• Desflurane, isoflurane, and sevoflurane provide limited neuroprotection against neonatal hypoxia-ischemia in a delayed preconditioning paradigm. 30 Aug 2009
• Spatial discrimination reversal learning in weanling rats is impaired by striatal administration of an NMDA-receptor antagonist. 25 Aug 2009
• Older and stronger object memories are selectively destabilized by reactivation in the presence of new information. 25 Aug 2009
• The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation. 25 Aug 2009
• Matrix metalloproteinases inhibition provides neuroprotection against hypoxia-ischemia in the developing brain. 25 Aug 2009
• NO-flurbiprofen reduces amyloid-beta, is neuroprotective in cell culture, and enhances cognition in response to cholinergic blockade. 19 Aug 2009
• Erythropoietin sustains cognitive function and brain volume after neonatal stroke. 9 Aug 2009
• Postischemic PKC activation rescues retrograde and anterograde long-term memory. 8 Aug 2009
• Possible involvement of GABAergic mechanism in protective effect of melatonin against sleep deprivation-induced behaviour modification and oxidative damage in mice. 30 Jul 2009
• Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood. 30 Jul 2009
• Hippocampal synapsin isoform levels are linked to spatial memory enhancement by SGS742. 30 Jul 2009
• Persistent short-term memory defects following sleep deprivation in a drosophila model of Parkinson disease. 30 Jul 2009
• Acute effect of Copaifera reticulata Ducke copaiba oil in rats tested in the elevated plus-maze: an ethological analysis. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Maze Learning'

Definition: Learning the correct route through a maze to obtain reinforcement. It is used for human or animal populations. (Thesaurus of Psychological Index Terms, 6th ed)

Descriptor UI: D018782

Alternative terms: Maze Learning; Learning, Maze; Learnings, Maze; Maze Learnings;

Allowable Qualifiers: classification; drug effects; physiology; radiation effects; ethics;

Tree Number: F02.463.425.507;

History Note: 95

Technical Notes: human & animal