Mediodorsal Thalamic Nucleus - Pathology
Research News and Information

Monday, November 23, 2009

Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop.

30 Oct 2009 OBJECTIVE: To describe structural and biochemical evidence from postmortem brains that implicates the reciprocal connections between the mediodorsal thalamic nucleus and the prefrontal cortex in cognitive symptoms of schizophrenia. METHOD: The ... Read more...

Selective reduction of neuron number and volume of the mediodorsal nucleus of the thalamus in macaques following irradiation at early gestational ages.

30 Jul 2009 Neurons in the macaque brain arise from progenitors located near the cerebral ventricles in a temporally segregated manner such that lethal doses of ionizing irradiation, if administered over a discrete time interval, can deplete individual nuclei ... Read more...

Thalamic damage in periventricular leukomalacia: novel pathologic observations relevant to cognitive deficits in survivors of prematurity.

29 Apr 2009 Despite major advances in the long-term survival of premature infants, cognitive deficits occur in 30-50% of very preterm (<32 gestational weeks) survivors. Impaired working memory and attention despite average global intelligence are central to the ... Read more...

Latest indexed articles for 'Mediodorsal Thalamic Nucleus - Pathology'

These are the very latest articles for this heading:

• Schizophrenia; from structure to function with special focus on the mediodorsal thalamic prefrontal loop. 30 Oct 2009
• Selective reduction of neuron number and volume of the mediodorsal nucleus of the thalamus in macaques following irradiation at early gestational ages. 30 Jul 2009
• Thalamic damage in periventricular leukomalacia: novel pathologic observations relevant to cognitive deficits in survivors of prematurity. 29 Apr 2009
• Resting state corticolimbic connectivity abnormalities in unmedicated bipolar disorder and unipolar depression. 18 Feb 2009
• Microvessel length density, total length, and length per neuron in five subcortical regions in schizophrenia. 4 Feb 2009
• Fiber tracking of white matter integrity connecting the mediodorsal nucleus of the thalamus and the prefrontal cortex in schizophrenia: a diffusion tensor imaging study. 2 Feb 2009
• Neurotoxic lesions of the thalamic reuniens or mediodorsal nucleus in rats affect non-mnemonic aspects of watermaze learning. 7 Jan 2009
• The mediodorsal thalamic nucleus and schizophrenia. 30 Oct 2008
• Changes in midline thalamic recruiting responses in the prefrontal cortex of the rat during the development of chronic limbic seizures. 15 Sep 2008
• Experimental petit mal-like seizure induced by microinjection of kainic acid into the unilateral mediodorsal nucleus of the thalamus. 29 Jun 2008
• Glial cell number and nuclear size in the mediodorsal thalamic nucleus (MDNT) in schizophrenia. 25 May 2008
• Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia. 25 Mar 2008
• Structural abnormalities of the adhesio interthalamica and mediodorsal nuclei of the thalamus in schizophrenia. 17 Feb 2008
• Preferential involvement of the basolateral limbic circuit in an amyotrophic lateral sclerosis patient. 29 Nov 2007
• Volume, neuron density and total neuron number in five subcortical regions in schizophrenia. 13 Feb 2007
• Diaschisis after thalamic stroke: a comparison of metabolic and structural changes in a patient with amnesic syndrome. 30 Dec 2006
• Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide. 13 Dec 2006
• [Morphogenetic effects of neonatal androgenization on neuron dendroarchitectonics in amygdala dorsomedial nucleus] 30 Aug 2006
• Abnormalities of thalamic activation and cognition in schizophrenia. 27 Feb 2006
• Volume and neuron number of the mediodorsal thalamic nucleus in schizophrenia: a replication study. 14 Nov 2005

See a longer list of these articles.

Technical information about 'Mediodorsal Thalamic Nucleus'

Definition: The largest of the medial nuclei of the thalamus. It makes extensive connections with most of the other thalamic nuclei.

Descriptor UI: D020645

Alternative terms: Mediodorsal Thalamic Nucleus; Nucleus, Mediodorsal Thalamic; Thalamic Nucleus, Mediodorsal; Mediodorsal Nucleus; Nucleus, Mediodorsal; Medial Dorsal Nucleus; Nucleus, Medial Dorsal; Dorsomedial Nucleus; Nucleus, Dorsomedial; Dorsal Medial Nucleus; Nucleus, Dorsal Medial; Dorsomedial Thalamic Nucleus; Nucleus, Dorsomedial Thalamic; Thalamic Nucleus, Dorsomedial;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.730.317.826.701.490;

History Note: 2000