Memantine - Classification
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Saturday, March 20, 2010

[Antidementia drugs]

30 May 2009 The pharmacological treatment of dementias aims to improve cognitive deficits, activities of daily living and behavioural and psychiatric symptoms. The weighting of theses therapeutic aims varies with disease progression. Behavioural symptoms may ... Read more...

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• [Antidementia drugs] 30 May 2009

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Technical information about 'Memantine'

Definition: AMANTADINE derivative that has some dopaminergic effects. It has been proposed as an antiparkinson agent.

Chemical name: Tricyclo(3.3.1.13,7)decan-1-amine, 3,5-dimethyl-

Registry Number: 19982-08-2

Descriptor UI: D008559

Alternative terms: Memantine; 1-Amino-3,5-dimethyladamantane; Memantin; 1,3-Dimethyl-5-aminoadamantane; Namenda; Ebixa; Lundbeck Brand of Memantine Hydrochloride; Memantine Hydrochloride; Axura; Merz Brand of Memantine Hydrochloride; D-145; D 145; D145;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Dopamine Agents; Excitatory Amino Acid Antagonists; Antiparkinson Agents;

Tree Number: D02.455.426.100.050.035.500;

Online Note: use MEMANTINE to search D 145 1976-83

History Note: 91(84); was see under AMANTADINE 1984-90; was D 145 see under AMANTADINE 1976-83