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Membrane Potentials - Physiology
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Definition of 'Membrane Potentials'

The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES' membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).

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Saturday, November 21, 2009

Rapid recycling of ClC-2 chloride channels between plasma membrane and endosomes: role of a tyrosine endocytosis motif in surface retrieval.

29 Nov 2009 ClC-2 chloride channel is present in the brain and some transporting epithelia where its function is poorly understood. We have now demonstrated that the surface channels are rapidly internalised and approximately the 70% of the surface membrane ... Read more...


Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons.

19 Oct 2009 The Mas-related G-protein-coupled receptor D (Mrgprd) marks a distinct subset of sensory neurons that transmit polymodal nociceptive information from the skin epidermis to the substantia gelatinosa (SG, lamina II) of the spinal cord. Moreover, ... Read more...


Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model.

19 Oct 2009 The B05 transgenic SCA1 mice, expressing human ataxin-1 with an expanded polyglutamine tract in cerebellar Purkinje cells (PCs), recapitulate many pathological and behavioral characteristics of the neurodegenerative disease spinocerebellar ataxia ... Read more...

 

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Technical information about 'Membrane Potentials'

Definition: The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES' membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).

Descriptor UI: D008564

Alternative terms: Membrane Potentials; Membrane Potential; Potential, Membrane; Potentials, Membrane; Transmembrane Potential Difference; Difference, Transmembrane Potential; Differences, Transmembrane Potential; Potential Difference, Transmembrane; Potential Differences, Transmembrane; Transmembrane Potential Differences; Transmembrane Electrical Potential Difference; Transmembrane Potentials; Potential, Transmembrane; Potentials, Transmembrane; Transmembrane Potential; Resting Potentials; Potential, Resting; Potentials, Resting; Resting Potential; Resting Membrane Potential; Membrane Potential, Resting; Membrane Potentials, Resting; Resting Membrane Potentials;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G01.154.535; G04.580; G07.265.750; G11.561.570;

History Note: 68(67)

Technical Notes: coordinate with organ /physiol

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