Membrane Proteins - Metabolism
Research News and Information

Saturday, November 21, 2009

Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability.

29 Nov 2009 Up to date, the nature of the sepsis-induced vascular leakage is understood only partially, which limits pharmacological approaches for its management. Here we studied the protective effect of cAMP using endotoxin-induced hyperpermeability as a ... Read more...

Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma.

13 Nov 2009 Antiangiogenic therapies are used for advanced clear-cell renal carcinomas (cRCC), but without curative possibilities, underlining the need for new therapeutic targets. Adrenomedullin (AM), a multifunctional peptide, is highly expressed in several ... Read more...

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

2 Nov 2009 Leucine-rich repeat kinase 2 (LRRK2) functions as a putative protein kinase of ezrin, radixin, and moesin (ERM) family proteins. A Parkinson's disease-related G2019S substitution in the kinase domain of LRRK2 further enhances the phosphorylation of ... Read more...

Latest indexed articles for 'Membrane Proteins - Metabolism'

These are the very latest articles for this heading:

• Molecular mechanisms mediating protective effect of cAMP on lipopolysaccharide (LPS)-induced human lung microvascular endothelial cells (HLMVEC) hyperpermeability. 29 Nov 2009
• Expression and role of adrenomedullin in renal tumors and value of its mRNA levels as prognostic factor in clear-cell renal carcinoma. 13 Nov 2009
• Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. 2 Nov 2009
• Redox characterization of the FeS protein MitoNEET and impact of thiazolidinedione drug binding. Nov 2009
• TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo. 30 Oct 2009
• Intestinal mucosal barrier function in health and disease. 30 Oct 2009
• NAG7 promotes human nasopharyngeal carcinoma invasion through inhibition of estrogen receptor alpha and up-regulation of JNK2/AP-1/MMP1 pathways. 30 Oct 2009
• Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. 27 Oct 2009
• Intra-axonal patterning: intrinsic compartmentalization of the axonal membrane in Drosophila neurons. 27 Oct 2009
• SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. 27 Oct 2009
• Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10. 21 Oct 2009
• Evidence against AMPA receptor-lacking glutamatergic synapses in the superficial dorsal horn of the rat spinal cord. 19 Oct 2009
• Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival. 18 Oct 2009
• Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains. 16 Oct 2009
• GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote budding. 14 Oct 2009
• TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling. 14 Oct 2009
• KIF5B motor adaptor syntabulin maintains synaptic transmission in sympathetic neurons. 12 Oct 2009
• Distinct domains within PSD-95 mediate synaptic incorporation, stabilization, and activity-dependent trafficking. 12 Oct 2009
• Environmental and intracellular regulation of Francisella tularensis ripA. 10 Oct 2009
• Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors. 10 Oct 2009

See a longer list of these articles.

Technical information about 'Membrane Proteins'

Definition: Proteins which are found in membranes including cellular and intracellular membranes. They consist of two types, peripheral and integral proteins. They include most membrane-associated enzymes, antigenic proteins, transport proteins, and drug, hormone, and lectin receptors.

Registry Number: 0

Descriptor UI: D008565

Alternative terms: Membrane Proteins; Proteins, Membrane; Surface Proteins; Proteins, Surface; Membrane-Associated Proteins; Membrane Associated Proteins; Proteins, Membrane-Associated; Membrane Protein; Protein, Membrane; Cell Surface Proteins; Proteins, Cell Surface; Integral Membrane Proteins; Membrane Proteins, Integral; Proteins, Integral Membrane; Integral Membrane Protein; Membrane Protein, Integral; Protein, Integral Membrane; Cell Membrane Proteins; Proteins, Cell Membrane;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.543;

History Note: 77

Technical Notes: /biosyn /drug eff /physiol /ultrastruct permitted