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Mental Retardation - Physiopathology
Research News and Information
Definition of 'Mental Retardation'Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28) |
Monday, November 23, 2009
Lower bispectral index values in children who are intellectually disabled.
30 Oct 2009 
BACKGROUND: Very few data are available on the use of bispectral index (BIS) monitoring in children who are intellectually disabled. Epileptiform electroencephalogram activity, underlying cerebral pathology, or anticonvulsant/spasmolytic therapy ... Read more...
Expanding the clinical and neuroradiologic phenotype of primary microcephaly due to ASPM mutations.
20 Sep 2009 OBJECTIVE: To determine the spectrum of clinical, neuropsychological, and neuroradiologic features in patients with autosomal recessive primary microcephaly (MCPH) due to ASPM gene mutations. METHODS: ASPM was sequenced in 52 unrelated MCPH ... Read more...
Focal cortical dysplasia type II: biological features and clinical perspectives.
30 Aug 2009 Focal cortical dysplasia (FCD) type II is an important cause of drug-resistant epilepsy. Clinical presentation is variable, and depends on age of onset of seizures and the location and size of lesion. As FCD type II cannot be diagnosed with ... Read more...
Latest indexed articles for 'Mental Retardation - Physiopathology'
These are the very latest articles for this heading:
- Lower bispectral index values in children who are intellectually disabled. 30 Oct 2009
- Expanding the clinical and neuroradiologic phenotype of primary microcephaly due to ASPM mutations. 20 Sep 2009
- Focal cortical dysplasia type II: biological features and clinical perspectives. 30 Aug 2009
- Disparate diseases due to copycat copy number variations.
30 Aug 2009 - Thyroid disorders in mental patients. 29 Jun 2009
- The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. 30 May 2009
- Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation.
26 Apr 2009 - Cognitive development and low-level lead exposure in poly-drug exposed children. 31 Mar 2009
- Postural stability of athletes in Special Olympics. 30 Mar 2009
- Increased aging in persons with intellectual disability in residential care centers in Israel 1999-2006. 30 Mar 2009
- Smith-Magenis syndrome with West syndrome in a 5-year-old girl: a long-term follow-up study. 2 Mar 2009
- Four Caucasian patients with mutations in the fukutin gene and variable clinical phenotype. 27 Feb 2009
- Physiological correlates of social avoidance behavior in children and adolescents with fragile x syndrome. 27 Feb 2009
- Hyperinsulinism in developmental syndromes. 25 Feb 2009
- Developmental syndromes: growth hormone deficiency and treatment. 25 Feb 2009
- [Correlation factors of electrical status epilepticus during sleep in children] 30 Jan 2009
- Infantile mitochondrial encephalomyopathy with unusual phenotype caused by a novel BCS1L mutation in an isolated complex III-deficient patient. 19 Jan 2009
- Early interventions involving parents to improve neurodevelopmental outcomes of premature infants: a meta-analysis. 13 Jan 2009
- Aerobic exercise improves lung function in children with intellectual disability: a randomised trial. 30 Dec 2008
- Blood parameters in adults with intellectual disability at rest and after endurance exercise. 30 Dec 2008
See a longer list of these articles.
Technical information about 'Mental Retardation'
Definition: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)
Descriptor UI: D008607
Alternative terms: Mental Retardation; Retardation, Mental; Idiocy; Deficiency, Mental; Deficiencies, Mental; Mental Deficiencies; Mental Deficiency; Mental Retardation, Psychosocial; Mental Retardations, Psychosocial; Psychosocial Mental Retardation; Psychosocial Mental Retardations; Retardation, Psychosocial Mental; Retardations, Psychosocial Mental;
Related Mesh Headings: Abnormalities, Multiple; Cockayne Syndrome; Congenital Hypothyroidism; Cri-du-Chat Syndrome; De Lange Syndrome; Down Syndrome; Education of Mentally Retarded; Fragile X Syndrome; Laurence-Moon Syndrome; Prader-Willi Syndrome; Rubinstein-Taybi Syndrome; Rett Syndrome; Angelman Syndrome; Williams Syndrome; Mentally Disabled Persons; Brain Diseases, Metabolic, Inborn; Bardet-Biedl Syndrome;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.597.606.643; C23.888.592.604.646; F01.700.687; F03.550.600;
History Note: 1967(1963)
Technical Notes: use Cat C qualif; /rehabil permitted: do not equate with EDUCATION OF MENTALLY RETARDED