Methoxyhydroxyphenylglycol - Metabolism
Research News and Information

Saturday, November 21, 2009

A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.

30 Jul 2009 BACKGROUND: The selective MAO-B inhibitor selegiline has been evaluated in clinical trials as a potential medication for the treatment of cocaine dependence. This study evaluated the safety of and pharmacologic interactions between 7 days of ... Read more...

Chapter 14. Biosynthesis of nonribosomal peptide precursors.

30 Dec 2008 Nonribosomal peptides are natural products typically of bacterial and fungal origin. These highly complex molecules display a broad spectrum of biological activities, and have been exploited for the development of immunosuppressant, antibiotic, ... Read more...

The effects of in utero exposure to a migrant, 4,4'-butylidenebis(6-t-butyl-m-cresol), from nitrile-butadiene rubber gloves on monoamine neurotransmitter in rats.

29 Nov 2008 4,4'-Butylidenebis(6-t-butyl-m-cresol) (BBBC) can be eluted from disposable gloves made of nitrile-butadiene rubber and possibly also detected in food. We have reported that BBBC is an androgen and estrogen antagonist. In this report, BBBC (0.1, 1.0 ... Read more...

Latest indexed articles for 'Methoxyhydroxyphenylglycol - Metabolism'

These are the very latest articles for this heading:

• A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion. 30 Jul 2009
• Chapter 14. Biosynthesis of nonribosomal peptide precursors. 30 Dec 2008
• The effects of in utero exposure to a migrant, 4,4'-butylidenebis(6-t-butyl-m-cresol), from nitrile-butadiene rubber gloves on monoamine neurotransmitter in rats. 29 Nov 2008
• Relationship between saliva level of 3-methoxy-4-hydroxyphenylglycol and mental health in the elderly general population. 29 Sep 2008
• Synergistic effects of psychological and immune stressors on inflammatory cytokine and sickness responses in humans. 18 Sep 2008
• Generalized and neurotransmitter-selective noradrenergic denervation in Parkinson's disease with orthostatic hypotension. 13 Sep 2008
• Neonatal N-(-2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) treatment modifies the vulnerability to phenobarbital- and ethanol-evoked sedative-hypnotic effects in adult rats. 29 Apr 2008
• Neonatal DSP-4 treatment modifies GABAergic neurotransmission in the prefrontal cortex of adult rats. 29 Apr 2008
• The integration of song environment by catecholaminergic systems innervating the auditory telencephalon of adult female European starlings. 30 Mar 2008
• Carnosine-induced antidepressant-like activity in rats. 2 Mar 2008
• Antidepressant-like effect of tramadol in the unpredictable chronic mild stress procedure: possible involvement of the noradrenergic system. 30 Oct 2007
• Neuroendocrine, behavioral and macrophage activity changes induced by picrotoxin effects in mice. 5 Oct 2007
• Pregabalin, S-(+)-3-isobutylgaba, activates the descending noradrenergic system to alleviate neuropathic pain in the mouse partial sciatic nerve ligation model. 17 Aug 2007
• Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: reduction by a selective serotonin reuptake inhibitor. 30 Jul 2007
• Disrupted dopaminergic neurotransmission in 22q11 deletion syndrome. 23 Jul 2007
• Effect of peripherally administered lipopolysaccharide (LPS) on GTP cyclohydrolase I, tetrahydrobiopterin and norepinephrine in the locus coeruleus in mice. 30 May 2007
• Climbing fiber-triggered metabotropic slow potentials enhance dendritic calcium transients and simple spike firing in cerebellar Purkinje cells. 22 May 2007
• Effects of methylphenidate on the hyperemotional behavior in olfactory bulbectomized mice by using the hole-board test. 12 Feb 2007
• Influence of poly I:C on sickness behaviors, plasma cytokines, corticosterone and central monoamine activity: moderation by social stressors. 28 Jan 2007
• Noradrenergic function in suicide. 30 Dec 2006

See a longer list of these articles.

Technical information about 'Methoxyhydroxyphenylglycol'

Definition: Synthesized from endogenous epinephrine and norepinephrine in vivo. It is found in brain, blood, CSF, and urine, where its concentrations are used to measure catecholamine turnover.

Chemical name: 1,2-Ethanediol, 1-(4-hydroxy-3-methoxyphenyl)-

Registry Number: 534-82-7

Descriptor UI: D008734

Alternative terms: Methoxyhydroxyphenylglycol; 4-Hydroxy-3-methoxyphenylethyleneglycol; 4 Hydroxy 3 methoxyphenylethyleneglycol; Vanylglycol; Hydroxymethoxyphenylglycol; MHPG; MOPEG; 4-Hydroxy-3-methoxyphenylethylene Glycol; 4 Hydroxy 3 methoxyphenylethylene Glycol; 4-Hydroxy-3-methoxyphenylglycol; 4 Hydroxy 3 methoxyphenylglycol; Methoxyhydroxyphenylglycol, (+-)-Isomer; Methoxyhydroxyphenylglycol, (-)-Isomer; Methoxyhydroxyphenylglycol, (+)-Isomer;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.033.455.250.610;

Online Note: use METHOXYHYDROXYPHENYLGLYCOL to search METHOXYHYDROXYPHENYL GLYCOL 1973-76 (as Prov 1973-74)

History Note: 91(77); was see under GLYCOLS 1977-90; was METHOXYHYDROXYPHENYL GLYCOL see under GLYCOLS 1975-76; was METHOXYHYDROXYPHENYL GLYCOL 1973-74 (Prov)