Methoxyhydroxyphenylglycol
Research News and Information

Sunday, November 08, 2009

Signal transduction mechanisms underlying group I mGluR-mediated increase in frequency and amplitude of spontaneous EPSCs in the spinal trigeminal subnucleus oralis of the rat.

31 Aug 2009 Group I mGluRs (mGluR1 and 5) pre- and/or postsynaptically regulate synaptic transmission at glutamatergic synapses. By recording spontaneous EPSCs (sEPSCs) in the spinal trigeminal subnucleus oralis (Vo), we here investigated the regulation of ... Read more...

A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion.

30 Jul 2009 BACKGROUND: The selective MAO-B inhibitor selegiline has been evaluated in clinical trials as a potential medication for the treatment of cocaine dependence. This study evaluated the safety of and pharmacologic interactions between 7 days of ... Read more...

Burst-timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons.

23 Jun 2009 Bursts of spikes triggered by sensory stimuli in midbrain dopamine neurons evoke phasic release of dopamine in target brain areas, driving reward-based reinforcement learning and goal-directed behavior. NMDA-type glutamate receptors (NMDARs) play a ... Read more...

Latest indexed articles for 'Methoxyhydroxyphenylglycol'

These are the very latest articles for this heading:

• Signal transduction mechanisms underlying group I mGluR-mediated increase in frequency and amplitude of spontaneous EPSCs in the spinal trigeminal subnucleus oralis of the rat. 31 Aug 2009
• A phase 1 trial of pharmacologic interactions between transdermal selegiline and a 4-hour cocaine infusion. 30 Jul 2009
• Burst-timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons. 23 Jun 2009
• DHPG activation of group 1 mGluRs in BLA enhances fear conditioning. 22 Jun 2009
• Subthreshold glutamate release from mitral cell dendrites. 25 May 2009
• Mobilization of calcium from intracellular stores facilitates somatodendritic dopamine release. 18 May 2009
• Converging signal on ERK1/2 activity regulates group I mGluR-mediated Arc transcription. 12 May 2009
• Glutamate-dependent transcriptional control in Bergmann glia: Sox10 as a repressor. 29 Apr 2009
• Separate signalling mechanisms underlie mGluR1 modulation of leak channels and NMDA receptors in the network underlying locomotion. 27 Apr 2009
• Jugular venous overflow of noradrenaline from the brain: a neurochemical indicator of cerebrovascular sympathetic nerve activity in humans. 27 Apr 2009
• Activation of metabotropic glutamate receptor 5 modulates microglial reactivity and neurotoxicity by inhibiting NADPH oxidase. 11 Apr 2009
• Endocannabinoid-mediated long-term depression in the avian midbrain expressed presynaptically and postsynaptically. 30 Mar 2009
• Association of MAOA gene functional promoter polymorphism with CSF dopamine turnover and atypical depression. 30 Mar 2009
• Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity. 4 Mar 2009
• Altered hippocampal synaptic plasticity in the FMR1 gene family knockout mouse models. 23 Feb 2009
• Relative efficiencies of plasma catechol levels and ratios for neonatal diagnosis of menkes disease. 19 Feb 2009
• MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs. 12 Feb 2009
• Distinct roles of metabotropic glutamate receptor activation on inhibitory signaling in the ventral lateral geniculate nucleus. 26 Jan 2009
• Chapter 14. Biosynthesis of nonribosomal peptide precursors. 30 Dec 2008
• Mechanisms of group I mGluR-dependent long-term depression of NMDA receptor-mediated transmission at Schaffer collateral-CA1 synapses. 22 Dec 2008

See a longer list of these articles.

Technical information about 'Methoxyhydroxyphenylglycol'

Definition: Synthesized from endogenous epinephrine and norepinephrine in vivo. It is found in brain, blood, CSF, and urine, where its concentrations are used to measure catecholamine turnover.

Chemical name: 1,2-Ethanediol, 1-(4-hydroxy-3-methoxyphenyl)-

Registry Number: 534-82-7

Descriptor UI: D008734

Alternative terms: Methoxyhydroxyphenylglycol; 4-Hydroxy-3-methoxyphenylethyleneglycol; 4 Hydroxy 3 methoxyphenylethyleneglycol; Vanylglycol; Hydroxymethoxyphenylglycol; MHPG; MOPEG; 4-Hydroxy-3-methoxyphenylethylene Glycol; 4 Hydroxy 3 methoxyphenylethylene Glycol; 4-Hydroxy-3-methoxyphenylglycol; 4 Hydroxy 3 methoxyphenylglycol; Methoxyhydroxyphenylglycol, (+-)-Isomer; Methoxyhydroxyphenylglycol, (-)-Isomer; Methoxyhydroxyphenylglycol, (+)-Isomer;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.033.455.250.610;

Online Note: use METHOXYHYDROXYPHENYLGLYCOL to search METHOXYHYDROXYPHENYL GLYCOL 1973-76 (as Prov 1973-74)

History Note: 91(77); was see under GLYCOLS 1977-90; was METHOXYHYDROXYPHENYL GLYCOL see under GLYCOLS 1975-76; was METHOXYHYDROXYPHENYL GLYCOL 1973-74 (Prov)