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Methylphenidate - Administration & dosage
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Definition of 'Methylphenidate'

A central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE.

Common names: Methylphenidate; Dexmethylphenidate; Dexmethylphenidate Hydrochloride; Hydrochloride, Dexmethylphenidate; Focalin; Novartis Pharmaceutical Brand of Dexmethylphenidate Hydrochloride; Metadate; Equasym; Celltech Brand of Methylphenidate Hydrochloride; Methylphenidate Hydrochloride

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Monday, November 23, 2009

A washout period needed before switching from a neuroleptic to an amphetamine.

30 Jul 2009 (1) Abrupt replacement of risperidone with methylphenidate can lead to severe agitation in children; (2) Abruptly switching from one pharmacological class to another can lead to ... Read more...


Behavioral response to methylphenidate challenge: influence of early life parental care.

29 Jun 2009 Rat studies have shown that pups subjected to suboptimal rearing conditions exhibited permanently dysregulated dopamine activity and altered behavioral responses to dopamine stimulation. In humans, heightened stress-induced mesoaccumbens dopamine ... Read more...


Side effects of methylphenidate in childhood cancer survivors: a randomized placebo-controlled trial.

29 Jun 2009 OBJECTIVES: To investigate the frequency and severity of side effects of methylphenidate among childhood survivors of acute lymphoblastic leukemia and brain tumors and identify predictors of higher adverse effect levels. METHODS: Childhood cancer ... Read more...

 

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Technical information about 'Methylphenidate'

Definition: A central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE.

Chemical name: 2-Piperidineacetic acid, alpha-phenyl-, methyl ester

Registry Number: 113-45-1

Descriptor UI: D008774

Alternative terms: Methylphenidate; Dexmethylphenidate; Dexmethylphenidate Hydrochloride; Hydrochloride, Dexmethylphenidate; Focalin; Novartis Pharmaceutical Brand of Dexmethylphenidate Hydrochloride; Metadate; Equasym; Celltech Brand of Methylphenidate Hydrochloride; Methylphenidate Hydrochloride; Hydrochloride, Methylphenidate; Phenidylate; Ritalin; Novartis Brand 1 of Methylphenidate Hydrochloride; Ritaline; Cephalon Brand of Methylphenidate Hydrochloride; Ritalin-SR; Ritalin SR; Novartis Brand 2 of Methylphenidate Hydrochloride; Tsentedrin; Centedrin; Daytrana; Methylin; Mallinckrodt Brand of Methylphenidate Hydrochloride;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Dopamine Uptake Inhibitors; Central Nervous System Stimulants;

Tree Number: D02.241.223.601.600; D03.383.621.460;

Online Note: use METHYLPHENIDATE to search PHENIDYLATE 1978-94

History Note: PHENIDYLATE was see METHYLPHENIDATE 1978-94

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