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Mice, Inbred BALB C
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Saturday, November 21, 2009

Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.

13 Dec 2009 BACKGROUND: Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the ... Read more...


Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts.

29 Nov 2009 The receptor activator of nuclear factor-kappaB ligand (RANKL) plays a critical role in the differentiation and bone resorptive activity of osteoclasts. Recently, the development of anti-resorptive agents from natural substances has become a subject ... Read more...


Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma.

29 Nov 2009 Our previous study has suggested that the cell cycle-related kinase (CCRK) is a putative candidate oncogene in glioblastoma tumorigenesis. The potential oncogenic role of CCRK and its clinical/prognostic significance, however, in ovarian carcinoma ... Read more...

 

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Technical information about 'Mice, Inbred BALB C'

Descriptor UI: D008807

Alternative terms: Mice, Inbred BALB C; BALB C Mouse, Inbred; Inbred BALB C Mice; Mouse, BALB C; BALB C Mouse; Mouse, Inbred BALB C; Mice, BALB C; BALB C Mice; BALB C Mice, Inbred; Inbred BALB C Mouse;

Allowable Qualifiers: abnormalities; anatomy & histology; blood; cerebrospinal fluid; classification; embryology; genetics; growth & development; immunology; injuries; metabolism; microbiology; parasitology; physiology; psychology; surgery; urine; virology;

Tree Number: B01.050.157.520.338; B01.050.199.520.520.338; B01.150.900.649.865.635.505.500.400.338;

History Note: 74(72)

Technical Notes: NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag MICE

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