Mice, Inbred Strains
Research News and Information

Monday, November 23, 2009

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

Ceramide metabolism determines glioma cell resistance to chemotherapy.

29 Nov 2009 Tumor cell resistance to chemotherapy constitutes a major problem in the treatment of malignant tumors. We here investigated the role of ceramide metabolism for the resistance of glioma cells to treatment with the chemotherapeutic drug, gemcitabine. ... Read more...

Influence of genetic background on fluoride metabolism in mice.

30 Oct 2009 A/J and 129P3/J mouse strains have different susceptibilities to dental fluorosis, due to their genetic backgrounds. This study tested whether these differences are due to variations in water intake and/or F metabolism. A/J (susceptible to dental ... Read more...

Latest indexed articles for 'Mice, Inbred Strains'

These are the very latest articles for this heading:

• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• Ceramide metabolism determines glioma cell resistance to chemotherapy. 29 Nov 2009
• Influence of genetic background on fluoride metabolism in mice. 30 Oct 2009
• Proteomic study of neuron and astrocyte cultures from senescence-accelerated mouse SAMP8 reveals degenerative changes. 5 Oct 2009
• Concomitant activation of P2Y(2) and P2Y(6) receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion. 29 Sep 2009
• Cell-autonomous role of EphB2 and EphB3 receptors in the thymic epithelial cell organization. 29 Sep 2009
• PolyI:C plus IL-2 or IL-12 induce IFN-gamma production by human NK cells via autocrine IFN-beta. 29 Sep 2009
• Development and maturation of invariant NKT cells in the presence of lysosomal engulfment. 29 Sep 2009
• Depletion of macrophages in mice results in higher dengue virus titers and highlights the role of macrophages for virus control. 29 Sep 2009
• Promoting MPhi transepithelial migration by stimulating the epithelial cell P2Y(2) receptor. 29 Sep 2009
• Forward genetics used to identify new gene Mon1a with critical role in controlling macrophage iron metabolism and iron recycling from erythrocytes. 29 Sep 2009
• Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. 29 Sep 2009
• Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin. 29 Sep 2009
• Effect of recombinant placental growth factor 2 on hypertension induced by full-length mouse soluble fms-like tyrosine kinase 1 adenoviral vector in pregnant mice. 26 Sep 2009
• Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice. 10 Sep 2009
• The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis. 6 Sep 2009
• Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3',4,4'-tetrachloroazobenzene for 2 years. 4 Sep 2009
• Inbred mouse strains differ in multiple hippocampal activity traits. 2 Sep 2009
• [Identification and classification of lysozyme-expressing cells in the mouse small intestinal crypt and their correlation with the morphology of secretory granules and labeling density of immunogold] 30 Aug 2009
• HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Mice, Inbred Strains'

Definition: Genetically identical individuals developed from brother and sister matings which have been carried out for twenty or more generations, or by parent x offspring matings carried out with certain restrictions. All animals within an inbred strain trace back to a common ancestor in the twentieth generation.

Descriptor UI: D008815

Alternative terms: Mice, Inbred Strains; Inbred Strain of Mouse; Mouse Inbred Strain; Mouse Inbred Strains; Mouse, Inbred Strain; Inbred Strain of Mice; Inbred Mouse Strains; Inbred Mouse Strain; Mouse Strain, Inbred; Mouse Strains, Inbred; Strain, Inbred Mouse; Strains, Inbred Mouse; Inbred Strains of Mice;

Allowable Qualifiers: abnormalities; anatomy & histology; blood; cerebrospinal fluid; classification; embryology; genetics; growth & development; immunology; injuries; metabolism; microbiology; parasitology; physiology; psychology; surgery; urine; virology;

Tree Number: B01.050.157.520; B01.050.199.520.520; B01.150.900.649.865.635.505.500.400;

History Note: 72

Technical Notes: GEN or unspecified; prefer specifics; NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag MICE; Manual 22.36