Mice, Transgenic
Research News and Information

Saturday, November 21, 2009

Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?

5 Dec 2009 Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of research in which a number of key technologies converge: in ... Read more...

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

Differential oncogenic potential of geographically distinct Helicobacter pylori CagA isoforms in mice.

29 Nov 2009 Infection with cagA-positive Helicobacter pylori is associated with gastric carcinoma. The cagA-encoded CagA protein is delivered into gastric epithelial cells and, upon tyrosine phosphorylation at the C-terminal EPIYA segments, binds and ... Read more...

Latest indexed articles for 'Mice, Transgenic'

These are the very latest articles for this heading:

• Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes? 5 Dec 2009
• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• Differential oncogenic potential of geographically distinct Helicobacter pylori CagA isoforms in mice. 29 Nov 2009
• Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. 2 Nov 2009
• Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. 2 Nov 2009
• Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. 2 Nov 2009
• Reticulon-4A (Nogo-A) redistributes protein disulfide isomerase to protect mice from SOD1-dependent amyotrophic lateral sclerosis. 2 Nov 2009
• Surface plasmon resonance binding kinetics of Alzheimer's disease amyloid beta peptide-capturing and plaque-binding monoclonal antibodies. Nov 2009
• TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo. 30 Oct 2009
• Isoflurane-induced changes in righting response and breathing are modulated by RGS proteins. 30 Oct 2009
• Osterix enhances BMSC-associated osseointegration of implants. 30 Oct 2009
• SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. 27 Oct 2009
• Mouse models of CNS embryonal tumors. 25 Oct 2009
• The development of the thalamic motor learning area is regulated by Fgf8 expression. 19 Oct 2009
• Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons. 19 Oct 2009
• Visual impairment in the absence of dystroglycan. 19 Oct 2009
• Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model. 19 Oct 2009
• Transposon-mediated BAC transgenesis in zebrafish and mice. 14 Oct 2009
• Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent. 14 Oct 2009
• Is antigen specificity of autoreactive T cells the key to islet entry? 14 Oct 2009

See a longer list of these articles.

Technical information about 'Mice, Transgenic'

Definition: Laboratory mice that have been produced from a genetically manipulated EGG or EMBRYO, MAMMALIAN.

Descriptor UI: D008822

Alternative terms: Mice, Transgenic; Mouse, Transgenic; Transgenic Mouse; Transgenic Mice; Founder Mice, Transgenic; Mice, Transgenic Founder; Transgenic Founder Mice; Mouse, Founder, Transgenic;

Allowable Qualifiers: abnormalities; anatomy & histology; blood; cerebrospinal fluid; classification; embryology; genetics; growth & development; immunology; injuries; metabolism; microbiology; parasitology; physiology; surgery; urine; virology;

Tree Number: B01.050.680.136.500; B01.150.900.649.865.635.505.500.800;

History Note: 88

Technical Notes: NIM with no qualifiers when experimental animal; check the tag MICE; for transgenic founder mice, coordinate with FOUNDER EFFECT