Mice
Research News and Information

Friday, November 20, 2009

Genetic complexity of absence seizures in substrains of C3H mice.

15 Dec 2009 Absence epilepsy is a common form of idiopathic generalized epilepsy whose etiology is poorly understood because of genetic and phenotypic heterogeneity. The inbred mouse strain C3H/He exhibits spontaneous absence seizures characterized by spike and ... Read more...

Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program.

13 Dec 2009 BACKGROUND: Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the ... Read more...

Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?

5 Dec 2009 Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of research in which a number of key technologies converge: in ... Read more...

Latest indexed articles for 'Mice'

These are the very latest articles for this heading:

• Genetic complexity of absence seizures in substrains of C3H mice. 15 Dec 2009
• Initial testing (stage 1) of the kinesin spindle protein inhibitor ispinesib by the pediatric preclinical testing program. 13 Dec 2009
• Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes? 5 Dec 2009
• Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). 29 Nov 2009
• Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells. 29 Nov 2009
• Osteoblast differentiation is functionally associated with decreased AMP kinase activity. 29 Nov 2009
• Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. 29 Nov 2009
• Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. 29 Nov 2009
• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• Ceramide metabolism determines glioma cell resistance to chemotherapy. 29 Nov 2009
• Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1. 29 Nov 2009
• Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity. 29 Nov 2009
• Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts. 29 Nov 2009
• Rapamycin impairs trabecular bone acquisition from high-dose but not low-dose intermittent parathyroid hormone treatment. 29 Nov 2009
• Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis. 29 Nov 2009
• Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma. 29 Nov 2009
• Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model. 29 Nov 2009
• Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. 29 Nov 2009
• Differential oncogenic potential of geographically distinct Helicobacter pylori CagA isoforms in mice. 29 Nov 2009
• Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway. 29 Nov 2009

See a longer list of these articles.

Technical information about 'Mice'

Definition: The common name for the genus Mus.

Descriptor UI: D051379

Alternative terms: Mice; Mus; Mouse; Mus musculus; Mouse, House; House Mouse; Mice, House; House Mice; Mus domesticus; domesticus, Mus; Mus musculus domesticus; domesticus, Mus musculus; musculus domesticus, Mus; Mice, Laboratory; Laboratory Mice; Mouse, Laboratory; Laboratory Mouse; Mouse, Swiss; Swiss Mouse; Swiss Mice; Mice, Swiss;

Allowable Qualifiers: abnormalities; anatomy & histology; blood; cerebrospinal fluid; classification; embryology; genetics; growth & development; immunology; injuries; metabolism; microbiology; parasitology; physiology; psychology; surgery; urine; virology;

Tree Number: B01.150.900.649.865.635.505.500;

History Note: 2006

Technical Notes: check tag: NIM no qualifiers for MICE, the genus MUS unspecified, or any MUS species