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Microdialysis
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Definition of 'Microdialysis'

A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.

Common names: Microdialysis

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Monday, November 23, 2009

Relationship between intracranial hemodynamics and microdialysis markers of energy metabolism and glutamate-glutamine turnover in patients with subarachnoid hemorrhage. Clinical article.

30 Oct 2009 OBJECT: The aim of this study was to explore the relationship between hemodynamics (intracranial and systemic) and brain tissue energy metabolism, and between hemodynamics and glutamate (Glt)-glutamine (Gln) cycle activity. METHODS: Brain ... Read more...


Prediction of antiepileptic drug efficacy: the use of intracerebral microdialysis to monitor biophase concentrations.

29 Sep 2009 Biophase concentrations of antiepileptic drugs can differ significantly from pharmacokinetics in plasma. A crucial determinant in the disposition of antiepileptic drugs to the brain is represented by the blood-brain barrier. There is growing ... Read more...


Basal forebrain lactate release and promotion of cortical arousal during prolonged waking is attenuated in aging.

14 Sep 2009 The wake-promoting basal forebrain (BF) is critically involved in sustaining cortical arousal. In the present study, we investigated how aging affects the capacity of the BF to cope with continuous activation during prolonged waking. Increased ... Read more...

 

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Technical information about 'Microdialysis'

Definition: A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.

Descriptor UI: D017551

Alternative terms: Microdialysis;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E05.196.353.500;

History Note: 94

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