Microfilament Proteins - Analysis
Research News and Information

Sunday, March 21, 2010

The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro.

6 Sep 2009 BACKGROUND: Fascin is overexpressed in many cancers, including colorectal, but its role in the malignant transformation of benign colorectal adenomas is unclear. METHODS: Immunohistochemical analysis of fascin expression was carried out in resected ... Read more...

A 2D-DIGE approach to identify proteins involved in inside-out control of integrins.

30 Jul 2009 Leukocyte integrins are functionally regulated by "inside-out" signaling, meaning that stimulus-induced signaling pathways act on the intracellular integrin tail and induce activation of the receptor at the outside. Both a change in conformation ... Read more...

Fibrillin-1 staining anomalies are associated with increased staining for TGF-beta and elastic fibre degradation; new clues to the pathogenesis of emphysema.

30 Jul 2009 We recently demonstrated aberrant staining of fibrillin-1 in lung tissue specimens with emphysematous lesions. In this study, we have extended this observation by an elaborate analysis of the elastic fibre. Using domain-specific antibodies to ... Read more...

Latest indexed articles for 'Microfilament Proteins - Analysis'

These are the very latest articles for this heading:

• The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro. 6 Sep 2009
• A 2D-DIGE approach to identify proteins involved in inside-out control of integrins. 30 Jul 2009
• Fibrillin-1 staining anomalies are associated with increased staining for TGF-beta and elastic fibre degradation; new clues to the pathogenesis of emphysema. 30 Jul 2009
• Quantitative determination of site-specific conformational distributions in an unfolded protein by solid-state nuclear magnetic resonance. 28 Jul 2009
• Reduction of Stat3 activity attenuates HIV-induced kidney injury. 14 Jul 2009
• Markers aiding the diagnosis of chondroid tumors: an immunohistochemical study including osteonectin, bcl-2, cox-2, actin, calponin, D2-40 (podoplanin), mdm-2, CD117 (c-kit), and YKL-40. 29 Jun 2009
• Changes in localization and expression levels of Shroom2 and spectrin contribute to variation in amphibian egg pigmentation patterns. 23 Jun 2009
• Lymphocyte depleted Hodgkin lymphoma: an evaluation with immunophenotyping and genetic analysis. 30 May 2009
• Coronin-1 is associated with neutrophil survival and is cleaved during apoptosis: potential implication in neutrophils from cystic fibrosis patients. 30 May 2009
• Immunohistochemical discrimination of plasmacytoid dendritic cells from myeloid dendritic cells in human pathological tissues. 29 Apr 2009
• Calponin is expressed in serous cystadenomas of the pancreas but not in adenocarcinomas or endocrine tumors. 29 Apr 2009
• Comparative protein expression profiles of hilar and peripheral hepatic cholangiocarcinomas. 23 Apr 2009
• Tumor microenvironment of metastasis in human breast carcinoma: a potential prognostic marker linked to hematogenous dissemination. 22 Mar 2009
• The genetic message of a sudden, unexpected death due to thoracic aortic dissection. 11 Mar 2009
• Fascin overexpression correlates with positive thrombospondin-1 and syndecan-1 expressions and a more aggressive clinical course in patients with gallbladder cancer. 2 Mar 2009
• Quantitative proteomic analysis of differential proteins in the stroma of nasopharyngeal carcinoma and normal nasopharyngeal epithelial tissue. 27 Feb 2009
• Actin, gelsolin and filamin-A are dynamic actors in the cytoskeleton remodelling contributing to the blood brain barrier phenotype. 27 Feb 2009
• Detection of fascin and CCR-7 positive mature dendritic cells in oral lichen planus. 18 Feb 2009
• Down-regulation of SM22/transgelin gene expression during H9c2 cells differentiation. 16 Feb 2009
• [Anatomy of the breast] 30 Jan 2009

See a longer list of these articles.

Technical information about 'Microfilament Proteins'

Definition: Filaments which are composed primarily of actin and found in the cytoplasmic matrix of almost all cells. They are often associated with microtubules and may play a role in cytoskeletal function and/or mediate movement of the cell or the organelles within the cell.

Registry Number: 0

Descriptor UI: D008840

Alternative terms: Microfilament Proteins; Proteins, Microfilament; Actin-Binding Proteins; Actin Binding Proteins; Proteins, Actin-Binding;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D05.750.078.730; D12.776.220.525;

History Note: 85

Technical Notes: /biosyn /drug eff /physiol /ultrastruct permitted