Migraine Disorders - Physiopathology
Research News and Information

Sunday, November 22, 2009

Neurological mechanisms of migraine: potential of the gap-junction modulator tonabersat in prevention of migraine.

30 Oct 2009 Migraine is a neurovascular disorder characterized by recurrent episodic headaches, and is caused by abnormal processing of sensory information due to peripheral and/or central sensitization. The exact pathophysiological mechanism underlying ... Read more...

Neurons of the dopaminergic/calcitonin gene-related peptide A11 cell group modulate neuronal firing in the trigeminocervical complex: an electrophysiological and immunohistochemical study.

5 Oct 2009 Activation of spinal trigeminal afferents innervating the cranial vasculature is likely to play a role in migraine, although some parts of the clinical presentation may have a dopaminergic basis. The A11 nucleus, located in the posterior ... Read more...

Randomized, controlled trial of telcagepant for the acute treatment of migraine.

20 Sep 2009 BACKGROUND: The neuropeptide calcitonin gene-related peptide (CGRP) plays a key role in migraine pathophysiology. In this large phase 3 clinical trial, we sought to confirm the efficacy of telcagepant, the first orally bioavailable CGRP receptor ... Read more...

Latest indexed articles for 'Migraine Disorders - Physiopathology'

These are the very latest articles for this heading:

• Neurological mechanisms of migraine: potential of the gap-junction modulator tonabersat in prevention of migraine. 30 Oct 2009
• Neurons of the dopaminergic/calcitonin gene-related peptide A11 cell group modulate neuronal firing in the trigeminocervical complex: an electrophysiological and immunohistochemical study. 5 Oct 2009
• Randomized, controlled trial of telcagepant for the acute treatment of migraine. 20 Sep 2009
• [Is there a bridge between migraine and familial mesial temporal lobe epilepsy?] 14 Sep 2009
• [Case of confusional migraine associated with transient increased blood flow in cerebral hemisphere] 30 Aug 2009
• Excessive acute migraine medication use and migraine progression. 30 Aug 2009
• Migraine and genetic and acquired vasculopathies. 30 Aug 2009
• Migraine as a systemic vasculopathy. 30 Aug 2009
• Interictal quantitative EEG in migraine: a blinded controlled study. 23 Aug 2009
• Vertigo as a migraine trigger. 23 Aug 2009
• Migraine and the hypothalamus. 30 Jul 2009
• Discussion. A placebo-controlled surgical trial of the treatment of migraine headaches. 30 Jul 2009
• A placebo-controlled surgical trial of the treatment of migraine headaches. 30 Jul 2009
• Transcranial Doppler study of cerebrovascular reactivity: are migraineurs more sensitive to breath-hold challenge? 23 Jul 2009
• Migraine during pregnancy: is it more than a headache? 12 Jul 2009
• Headaches in the different phases of relapsing-remitting multiple sclerosis: a tendency for stabbing headaches during relapses. 29 Jun 2009
• Migraine, valproic acid, and lipoprotein(a). 29 Jun 2009
• Origin of pain in migraine: evidence for peripheral sensitisation. 29 Jun 2009
• Excitatory neurotransmitters in brain regions in interictal migraine patients. 28 Jun 2009
• Variations in the cannabinoid receptor 1 gene predispose to migraine. 15 Jun 2009

See a longer list of these articles.

Technical information about 'Migraine Disorders'

Definition: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Descriptor UI: D008881

Alternative terms: Migraine Disorders; Disorder, Migraine; Disorders, Migraine; Migraine Disorder; Migraine; Migraines; Migraine Headache; Headache, Migraine; Headaches, Migraine; Migraine Headaches; Acute Confusional Migraine; Acute Confusional Migraines; Migraine, Acute Confusional; Migraines, Acute Confusional; Status Migrainosus; Hemicrania Migraine; Hemicrania Migraines; Migraine, Hemicrania; Migraines, Hemicrania; Migraine Variant; Migraine Variants; Variant, Migraine; Variants, Migraine; Sick Headache; Headache, Sick; Headaches, Sick; Sick Headaches; Abdominal Migraine; Abdominal Migraines; Migraine, Abdominal; Migraines, Abdominal; Cervical Migraine Syndrome; Cervical Migraine Syndromes; Migraine Syndrome, Cervical; Migraine Syndromes, Cervical;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.546.399.750;

History Note: 2006 (1963)

Technical Notes: note many specifics; use word of text