Mitogen-Activated Protein Kinase 1 - Analysis
Research News and Information

Monday, November 23, 2009

Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content.

21 Jun 2009 Acute contractile activity increases the activation of protein kinases involved in signal transduction. We hypothesized that the contractile activity-induced kinase phosphorylation would occur to a lesser degree in muscle with elevated mitochondrial ... Read more...

Glycogen synthase kinase 3B in bovine oocytes and granulosa cells: possible involvement in meiosis during in vitro maturation.

19 May 2009 Glycogen synthase kinase 3 (GSK3) regulates cellular metabolism and cell cycle via different signalling pathways. In response to insulin and growth factors GSK3 is serine-phosphorylated and inactivated. We analysed GSK3B expression and activation in ... Read more...

Measurement of phosphorylated extracellular signal-regulated kinase 1 and 2 in an undergraduate teaching laboratory with ALPHAscreen technology.

15 Mar 2009 Teaching the practical aspects of signal transduction to large undergraduate classes can be challenging when there is only a finite time frame in which to engage in laboratory activities. This teaching resource describes the use of bead-based ... Read more...

Latest indexed articles for 'Mitogen-Activated Protein Kinase 1 - Analysis'

These are the very latest articles for this heading:

• Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content. 21 Jun 2009
• Glycogen synthase kinase 3B in bovine oocytes and granulosa cells: possible involvement in meiosis during in vitro maturation. 19 May 2009
• Measurement of phosphorylated extracellular signal-regulated kinase 1 and 2 in an undergraduate teaching laboratory with ALPHAscreen technology. 15 Mar 2009
• Analysis of protein phosphorylation by monolithic extraction columns based on poly(divinylbenzene) containing embedded titanium dioxide and zirconium dioxide nano-powders. 30 Oct 2008
• Treponema denticola peptidoglycan induces the production of inflammatory mediators and matrix metalloproteinase 9 in macrophage-like cells. 20 Oct 2008
• Effects of heparin-binding epidermal growth factor-like growth factor on cell repopulation and signal transduction in periodontal ligament cells after scratch wounding in vitro. 5 Oct 2008
• Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death. 15 Jul 2008
• Lithium-induced suppression of transcription repressor NRSF/REST: effects on the dysfunction of neuronal differentiation by ethanol. 15 Jul 2008
• Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. 14 Apr 2008
• Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling. 30 Mar 2008
• A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein-coupled receptor 30 in some brain areas of the hamster. 30 Dec 2007
• An optimized immunohistochemical method for detection of phosphorylated mitogen-activated protein kinases. 24 Nov 2007
• Topical matrix-based siRNA silences local gene expression in a murine wound model. 10 Jul 2007
• Application of hydrogen/deuterium exchange mass spectrometry to study protein tyrosine phosphatase dynamics, ligand binding, and substrate specificity. 29 Jun 2007
• Effect of an oily calcium hydroxide suspension (Osteoinductal) on human periodontal fibroblasts. An in vitro study. 25 Jun 2007
• Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids. 10 Jun 2007
• Survival signaling and terminal differentiation in cholesteatoma epithelium. 30 Mar 2007
• Soluble products from Eikenella corrodens induce cell proliferation and expression of interleukin-8 and adhesion molecules in endothelial cells via mitogen-activated protein kinase pathways. 30 Jan 2007
• Activation of c-jun N-terminal kinase is associated with cell proliferation and shorter relapse-free period in superficial spreading malignant melanoma. 30 Aug 2006
• EGFR is phosphorylated at Ty845 in hepatocellular carcinoma. 23 Aug 2006

See a longer list of these articles.

Technical information about 'Mitogen-Activated Protein Kinase 1'

Definition: A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms.

Registry Number: EC 2.7.1.37

Descriptor UI: D019950

Alternative terms: Mitogen-Activated Protein Kinase 1; Mitogen Activated Protein Kinase 1; Extracellular Signal-Regulated Kinase 2; Extracellular Signal Regulated Kinase 2; MAP Kinase 2; MAPK1 Mitogen-Activated Protein Kinase; MAPK1 Mitogen Activated Protein Kinase; p42(Mitogen-Activated Protein Kinase); Mitogen-Activated Protein Kinase 2; Mitogen Activated Protein Kinase 2; p42 MAP Kinase; MAP Kinase, p42; p42(Mapk); p42(Mapk) Kinase; p42 MAPK; MAPK2 Mitogen-Activated Protein Kinase; MAPK2 Mitogen Activated Protein Kinase; p41 Mitogen-Activated Protein Kinase; p41 Mitogen Activated Protein Kinase; p41 MAPK; p40 Mitogen-Activated Protein Kinase; p40 Mitogen Activated Protein Kinase; ERK2 Brain Kinase PK40;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.913.696.620.682.700.567.342.500; D08.811.913.696.620.682.700.646.750.249.500; D12.644.360.450.169.500; D12.776.476.450.169.500;

History Note: 2005(1992)

Technical Notes: Don't confuse MAP Kinase 2 with MAP KINASE KINASES referred to as MAP2 Kinases