Models, Animal
Research News and Information

Saturday, November 21, 2009

Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability.

2 Nov 2009 The effects of lifelong, moderate excess release of glutamate (Glu) in the CNS have not been previously characterized. We created a transgenic (Tg) mouse model of lifelong excess synaptic Glu release in the CNS by introducing the gene for glutamate ... Read more...

The effects of electroacupuncture on TH1/TH2 cytokine mRNA expression and mitogen-activated protein kinase signaling pathways in the splenic T cells of traumatized rats.

30 Oct 2009 BACKGROUND: Surgical trauma contributes to postoperative immune suppression, which is associated with an increased susceptibility to subsequent infections. Electroacupuncture (EA) can alleviate pain and exert immunoregulatory effects. However, the ... Read more...

How a US regulator can encourage new science.

30 Oct 2009 The Center for Drug Evaluation and Research at the US Food and Drug Administration (FDA) is developing a process to qualify biomarkers for use under particular conditions. As part of this effort, Goodsaid et al. have carried out work, described in ... Read more...

Latest indexed articles for 'Models, Animal'

These are the very latest articles for this heading:

• Clinical models of tolerance induction in pediatric transplantation. 17 Nov 2009
• Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. 2 Nov 2009
• The effects of electroacupuncture on TH1/TH2 cytokine mRNA expression and mitogen-activated protein kinase signaling pathways in the splenic T cells of traumatized rats. 30 Oct 2009
• How a US regulator can encourage new science. 30 Oct 2009
• The human skin/chick chorioallantoic membrane model accurately predicts the potency of cosmetic allergens. 21 Oct 2009
• Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery. 18 Oct 2009
• Maternal high-fat diet promotes body length increases and insulin insensitivity in second-generation mice. 7 Oct 2009
• Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury. 6 Oct 2009
• Anterior cervical discectomy and fusion in the ovine model. 3 Oct 2009
• Considerations for reducing the euthanasia procedure in toxicological studies of biopharmaceuticals using non-human primates. 29 Sep 2009
• Biological effects of high-energy neutrons measured in vivo using a vertebrate model. 29 Sep 2009
• Animal models and different therapies for treatment of retinitis pigmentosa. 29 Sep 2009
• Descemet stripping automated endothelial keratoplasty using cultured corneal endothelial cells in a rabbit model. 29 Sep 2009
• Wireless Instantaneous Neurotransmitter Concentration System-based amperometric detection of dopamine, adenosine, and glutamate for intraoperative neurochemical monitoring. 29 Sep 2009
• Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. 29 Sep 2009
• Trains of transcranial direct current stimulation antagonize motor cortex hypoexcitability induced by acute hemicerebellectomy. 29 Sep 2009
• A model for 532-nanometer pulsed potassium titanyl phosphate (KTP) laser-induced injury in the rat larynx. 29 Sep 2009
• Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice. 29 Sep 2009
• Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis. 29 Sep 2009
• Airway-specific recruitment of T cells is reduced in a CD26-deficient F344 rat substrain. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Models, Animal'

Definition: Non-human animals, selected because of specific characteristics, for use in experimental research, teaching, or testing.

Descriptor UI: D023421

Alternative terms: Models, Animal; Animal Model; Animal Models; Model, Animal; Laboratory Animal Models; Animal Model, Laboratory; Animal Models, Laboratory; Laboratory Animal Model; Model, Laboratory Animal; Models, Laboratory Animal; Experimental Animal Models; Animal Model, Experimental; Animal Models, Experimental; Experimental Animal Model; Model, Experimental Animal; Models, Experimental Animal;

Related Mesh Headings: Animal Experimentation;

Tree Number: E05.598;

History Note: 2001