Morphine
Research News and Information

Saturday, November 21, 2009

Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study).

30 Oct 2009 BACKGROUND: Commonly used sedatives/analgesics can increase the risk of postoperative complications, including delirium. This double-blinded study assessed the neurobehavioral, hemodynamic, and sedative characteristics of dexmedetomidine compared ... Read more...

Central sensory-motor deficit after uneventful single-dose spinal morphine administration in a patient with preexisting migraine headaches.

30 Oct 2009 Hemiplegic migraine is a condition associated with vascular alteration of the central nervous system and transient neurologic deficits. Permanent morphine-induced motor dysfunction has been reported after spinal ischemia. We report a persisting ... Read more...

A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy.

30 Oct 2009 BACKGROUND: Gabapentin and ketamine are popular analgesic adjuvants for improving perioperative pain management. We designed this double-blind, placebo-controlled study to test and compare the preventive effects of perioperative ketamine and ... Read more...

Latest indexed articles for 'Morphine'

These are the very latest articles for this heading:

• Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study). 30 Oct 2009
• Continuous transversus abdominis plane block for renal transplant recipients. 30 Oct 2009
• Central sensory-motor deficit after uneventful single-dose spinal morphine administration in a patient with preexisting migraine headaches. 30 Oct 2009
• A comparison of gabapentin and ketamine in acute and chronic pain after hysterectomy. 30 Oct 2009
• A randomized controlled trial of pentazocine versus ondansetron for the treatment of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. 30 Oct 2009
• A randomized comparison of low doses of hyperbaric bupivacaine in combined spinal-epidural anesthesia for cesarean delivery. 30 Oct 2009
• Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion. 30 Oct 2009
• Craniotomy pain: trying to do better. 30 Oct 2009
• T-type calcium channel inhibition underlies the analgesic effects of the endogenous lipoamino acids. 19 Oct 2009
• No brain, no pain: does the injured brain stack up opioids? 29 Sep 2009
• Effect of acute inflammatory brain injury on accumulation of morphine and morphine 3- and 6-glucuronide in the human brain. 29 Sep 2009
• Nuclear expression of mu-opioid receptors in a human mesothelial cell line. 29 Sep 2009
• Commentary. 29 Sep 2009
• Commentary. 29 Sep 2009
• Unexpected urine drug testing results in a hospice patient on high-dose morphine therapy. 29 Sep 2009
• The synergistic interaction between morphine and maprotiline after intrathecal injection in rats. 29 Sep 2009
• A comparison of intravenous oxycodone and intravenous morphine in patient-controlled postoperative analgesia after laparoscopic hysterectomy. 29 Sep 2009
• Pediatric nurses' thinking in response to vignettes on administering analgesics. 29 Sep 2009
• Effects of morphine on testosterone levels in rat C6 glioma cells: modulation by anastrozole. 29 Sep 2009
• Involvement of actin rearrangements within the amygdala and the dorsal hippocampus in aversive memories of drug withdrawal in acute morphine-dependent rats. 28 Sep 2009

See a longer list of these articles.

Technical information about 'Morphine'

Definition: The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.

Chemical name: Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-

Registry Number: 57-27-2

Descriptor UI: D009020

Alternative terms: Morphine; Morphia; Morphine Chloride; Chloride, Morphine; Morphine Sulfate; Sulfate, Morphine; SDZ 202-250; SDZ 202 250; SDZ 202250; SDZ202-250; SDZ202 250; SDZ202250; Morphine Sulfate (2:1), Pentahydrate; MS Contin; Contin, MS; Oramorph SR; Duramorph; Morphine Sulfate (2:1), Anhydrous;

Related Mesh Headings: Receptors, Opioid;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis;

Pharmacological Action: Analgesics, Opioid; Narcotics;

Tree Number: D03.132.577.249.547; D03.549.686.575; D03.605.497.575; D04.615.723.795.547;

History Note: MORPHINE SULFATE was (NM) 1980-96

Technical Notes: /analogs = MORPHINE DERIVATIVES