Multicenter Studies as Topic
Research News and Information

Monday, November 23, 2009

Baseline characteristics and statistical power in randomized controlled trials: selection, prognostic targeting, or covariate adjustment?

29 Sep 2009 OBJECTIVE: Heterogeneity of patients is a common problem in randomized controlled trials (RCTs) in various fields of clinical research. We aimed to investigate the potential benefits of different approaches for dealing with heterogeneity in a case ... Read more...

Clinical trials design lessons from the CATIE study.

29 Sep 2009 The Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) study was funded by the National Institute of Mental Health to compare the effectiveness of drugs for schizophrenia. The focus here is not on its conclusions but on the knotty ... Read more...

Baseline differences in the HF-ACTION trial by sex.

29 Sep 2009 BACKGROUND: In patients with heart failure (HF), assessment of functional capacity plays an important prognostic role. Both 6-minute walk and cardiopulmonary exercise testing have been used to determine physical function and to determine prognosis ... Read more...

Latest indexed articles for 'Multicenter Studies as Topic'

These are the very latest articles for this heading:

• Bleak prospects for primary progressive multiple sclerosis therapy: downs and downs, but a glimmer of hope. 29 Sep 2009
• Can the WATCHMAN device truly PROTECT from stroke in atrial fibrillation? 29 Sep 2009
• Baseline characteristics and statistical power in randomized controlled trials: selection, prognostic targeting, or covariate adjustment? 29 Sep 2009
• Clinical trials design lessons from the CATIE study. 29 Sep 2009
• Baseline differences in the HF-ACTION trial by sex. 29 Sep 2009
• Understanding heart failure through the HF-ACTION baseline characteristics. 29 Sep 2009
• A prediction model for out-of-hospital cardiopulmonary resuscitation. 29 Sep 2009
• Chemotherapy-induced neutropenia as a prognostic factor in advanced non-small-cell lung cancer: results from Japan Multinational Trial Organization LC00-03. 27 Sep 2009
• QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali. 16 Sep 2009
• Gastric cancer: trastuzumab trial results spur search for other targets. 13 Sep 2009
• Method for establishing authorship in a multicenter clinical trial. 13 Sep 2009
• Noninvasive MR imaging of cerebral perfusion in patients with a carotid artery stenosis. 13 Sep 2009
• Monitoring ovarian cancer: CA125 trial stirs controversy. 6 Sep 2009
• A case study evaluation of ethics review systems for multicentre clinical trials. 5 Sep 2009
• Trials of diminishing relapses for diminishing returns. 31 Aug 2009
• [The assessment of Attention Deficit Hyperactivity Disorder (ADHD) by teacher ratings - validity and reliability of the FBB-HKS] 30 Aug 2009
• Women's experiences of participating in the Magpie Trial: a postal survey in the United Kingdom. 30 Aug 2009
• Hematology: Azacitidine improves survival in myelodysplastic syndromes. 30 Aug 2009
• Serum osteopontin levels are highly prognostic for survival in advanced non-small cell lung cancer: results from JMTO LC 0004. 30 Aug 2009
• Bringing arts-based therapies in from the scientific cold. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Multicenter Studies as Topic'

Definition: Controlled studies which are planned and carried out by several cooperating institutions to assess certain variables and outcomes in specific patient populations, for example, a multicenter study of congenital anomalies in children.

Descriptor UI: D015337

Alternative terms: Multicenter Studies as Topic; Multicentre Studies as Topic; Multicenter Trials; Multicenter Trial; Trial, Multicenter; Trials, Multicenter; Multicentre Trials; Multicentre Trial; Trial, Multicentre; Trials, Multicentre;

Related Mesh Headings: Clinical Trials, Phase III as Topic; Clinical Trials, Phase IV as Topic;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics; legislation & jurisprudence;

Tree Number: E05.318.760.535.500; E05.337.250.500; N05.715.360.775.235.545; N06.850.520.450.535.500;

History Note: 2008(1989)

Technical Notes: for general design, methodology, economics, etc. of multicenter studies; a different heading MULTICENTER STUDIES is used for reports of a specific multicenter study; specify geographic term if pertinent