Muscle, Skeletal - Enzymology
Research News and Information

Sunday, November 22, 2009

[Pompe's disease. Part II. Treatment strategies and enzyme replacement]

28 Sep 2009 Pompe's disease is an ultra-orphan disease caused by the deficiency of lysosomal alpha-glucosidase. At present, it is the only inherited muscle disorder, which can be treated by replacement of the enzyme. Three international randomized trials ... Read more...

A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload.

16 Sep 2009 A high-fat diet can increase adiposity, leptin secretion, and plasma fatty acid concentration. In hypertension, this scenario may accelerate cardiac hypertrophy and development of heart failure but could be protective by activating peroxisome ... Read more...

Modulation of myocellular fat stores: lipid droplet dynamics in health and disease.

17 Aug 2009 Storage of fatty acids as triacylglycerol (TAG) occurs in almost all mammalian tissues. Whereas adipose tissue is by far the largest storage site of fatty acids as TAG, subcellular TAG-containing structures--referred to as lipid droplets (LD)--are ... Read more...

Latest indexed articles for 'Muscle, Skeletal - Enzymology'

These are the very latest articles for this heading:

• [Pompe's disease. Part II. Treatment strategies and enzyme replacement] 28 Sep 2009
• A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload. 16 Sep 2009
• Modulation of myocellular fat stores: lipid droplet dynamics in health and disease. 17 Aug 2009
• Down-regulation of lipoprotein lipase increases glucose uptake in L6 muscle cells. 17 Aug 2009
• Single-molecule force spectroscopy distinguishes target binding modes of calmodulin. 8 Aug 2009
• A heterozygous truncating mutation in RRM2B causes autosomal-dominant progressive external ophthalmoplegia with multiple mtDNA deletions. 4 Aug 2009
• Skeletal muscle deiodinase type 2 regulation during illness in mice. 3 Aug 2009
• Effects of ovariectomy and resistance training on MMP-2 activity in skeletal muscle. 30 Jul 2009
• Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase. 30 Jul 2009
• 3-hydroxy 3-methylglutaryl coenzyme A reductase increase is essential for rat muscle differentiation. 30 Jul 2009
• Aging-associated dysfunction of Akt/protein kinase B: S-nitrosylation and acetaminophen intervention. 27 Jul 2009
• Muscle glycogenosis due to phosphoglucomutase 1 deficiency. 21 Jul 2009
• FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle. 20 Jul 2009
• Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity. 20 Jul 2009
• Adaptations to high-intensity intermittent exercise in rodents. 14 Jul 2009
• Caffeine acutely activates 5'adenosine monophosphate-activated protein kinase and increases insulin-independent glucose transport in rat skeletal muscles. 13 Jul 2009
• Prior heavy exercise elevates pyruvate dehydrogenase activity and muscle oxygenation and speeds O2 uptake kinetics during moderate exercise in older adults. 13 Jul 2009
• Modulation of SERCA in the chronic phase of adjuvant arthritis as a possible adaptation mechanism of redox imbalance. 6 Jul 2009
• The effect of muscle phospholipid fatty acid composition on exercise performance: a direct test in the migratory white-throated sparrow (Zonotrichia albicollis). 6 Jul 2009
• Decreased enzyme activity and contents of hepatic branched-chain alpha-keto acid dehydrogenase complex subunits in a rat model for type 2 diabetes mellitus. 5 Jul 2009

See a longer list of these articles.

Technical information about 'Muscle, Skeletal'

Definition: A subtype of striated muscle, attached by TENDONS to the SKELETON. Skeletal muscles are innervated and their movement can be consciously controlled. They are also called voluntary muscles.

Descriptor UI: D018482

Alternative terms: Muscle, Skeletal; Muscles, Skeletal; Skeletal Muscles; Skeletal Muscle; Muscle, Voluntary; Muscles, Voluntary; Voluntary Muscle; Voluntary Muscles; Soleus Muscle; Muscle, Soleus; Plantaris Muscle; Muscle, Plantaris; Anterior Tibial Muscle; Muscle, Anterior Tibial; Tibial Muscle, Anterior; Gastrocnemius Muscle; Muscle, Gastrocnemius;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; innervation; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A02.633.567; A10.690.552.500;

History Note: 95

Technical Notes: /growth: coordinate with MUSCLE DEVELOPMENT; /embryol: coordinate with MUSCLE DEVELOPMENT if pertinent