Muscular Diseases
Research News and Information

Saturday, November 21, 2009

The SLCO1B1*5 genetic variant is associated with statin-induced side effects.

18 Oct 2009 OBJECTIVES: We sought to identify single nucleotide polymorphisms associated with mild statin-induced side effects. BACKGROUND: Statin-induced side effects can interfere with therapy. Single nucleotide polymorphisms in cytochrome P450 enzymes impair ... Read more...

A RYR1 mutation associated with recessive congenital myopathy and dominant malignant hyperthermia in Asian families.

29 Sep 2009 In this study we present 3 families with malignant hyperthermia (MH), all of Indian subcontinent descent. One individual from each of these families was fully sequenced for RYR1 and presented with the non-synonymous change c.11315G>A/p.R3772Q. When ... Read more...

Adductor-related groin pain in recreational athletes: role of the adductor enthesis, magnetic resonance imaging, and entheseal pubic cleft injections.

29 Sep 2009 BACKGROUND: Adductor dysfunction can cause groin pain in athletes and may emanate from the adductor enthesis. Adductor enthesopathy may be visualized with magnetic resonance imaging and may be treated with entheseal pubic cleft injections. We have ... Read more...

Latest indexed articles for 'Muscular Diseases'

These are the very latest articles for this heading:

• The pharmacogenetics of statin therapy: when the body aches, the mind will follow. 18 Oct 2009
• The SLCO1B1*5 genetic variant is associated with statin-induced side effects. 18 Oct 2009
• Response to Dr. Miller. 11 Oct 2009
• A RYR1 mutation associated with recessive congenital myopathy and dominant malignant hyperthermia in Asian families. 29 Sep 2009
• Pathology in practice. Severe multifocal to locally extensive, monophasic skeletal muscle necrosis and multifocal, monophasic myocardial necrosis. 29 Sep 2009
• Adductor-related groin pain in recreational athletes: role of the adductor enthesis, magnetic resonance imaging, and entheseal pubic cleft injections. 29 Sep 2009
• Muscle deficits in cerebral palsy and early loss of mobility: can we learn something from our elders? 29 Sep 2009
• Core myopathies and risk of malignant hyperthermia. 29 Sep 2009
• Malignant hyperthermia-associated diseases: state of the art uncertainty. 29 Sep 2009
• The association of malignant hyperthermia and unusual disease: when you're hot you're hot or maybe not. 29 Sep 2009
• Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions. 28 Sep 2009
• Fear of statins? 13 Sep 2009
• [Lower and lower cholesterol targets increase adverse effects] 30 Aug 2009
• [Warning for simvastatin 80 mg!] 30 Aug 2009
• [Myopathy in the course of hypolipemic theraphy in patient undergoing early cardiac rehabilitation after the percutaneous coronary intervention--a case report] 30 Aug 2009
• Mutations and polymorphisms of the skeletal muscle alpha-actin gene (ACTA1). 30 Aug 2009
• Intragenic deletion of TRIM32 in compound heterozygotes with sarcotubular myopathy/LGMD2H. 30 Aug 2009
• Imaging of the musculoskeletal system in vivo using ultra-high field magnetic resonance at 7 T. 30 Aug 2009
• An unusual complication: prolonged myopathy due to an alternative medical therapy with heat and massage. 30 Aug 2009
• A case of rectus sheath hematoma caused by yoga exercise. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Muscular Diseases'

Definition: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Descriptor UI: D009135

Alternative terms: Muscular Diseases; Muscular Disease; Myopathies; Myopathy; Muscle Disorders; Muscle Disorder; Myopathic Conditions; Myopathic Condition;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C05.651; C10.668.491;

Technical Notes: GEN; prefer specifics; inflamm dis = MYOSITIS. /congen: consider also Myopathies, Structural, Congenital & its indentions