Mutagenesis, Insertional - Genetics
Research News and Information

Sunday, November 22, 2009

Selective epigenetic control of retrotransposition in Arabidopsis.

4 Sep 2009 Retrotransposons are mobile genetic elements that populate chromosomes, where the host largely controls their activities. In plants and mammals, retrotransposons are transcriptionally silenced by DNA methylation, which in Arabidopsis is propagated ... Read more...

Bursts of retrotransposition reproduced in Arabidopsis.

4 Sep 2009 Retrotransposons, which proliferate by reverse transcription of RNA intermediates, comprise a major portion of plant genomes. Plants often change the genome size and organization during evolution by rapid proliferation and deletion of long terminal ... Read more...

Adaptive evolution involving gene duplication and insertion of a novel Ty1/copia-like retrotransposon in soybean.

21 Jul 2009 Gene duplication is a major force for generating evolutionary novelties that lead to adaptations to environments. We previously identified two paralogs encoding phytochrome A (phyA), GmphyA1 and GmphyA2, in soybean, a paleopolyploid species. GmphyA2 ... Read more...

Latest indexed articles for 'Mutagenesis, Insertional - Genetics'

These are the very latest articles for this heading:

• Selective epigenetic control of retrotransposition in Arabidopsis. 4 Sep 2009
• Bursts of retrotransposition reproduced in Arabidopsis. 4 Sep 2009
• Adaptive evolution involving gene duplication and insertion of a novel Ty1/copia-like retrotransposon in soybean. 21 Jul 2009
• Genomewide association between insertions/deletions and the nucleotide diversity in bacteria. 6 Jul 2009
• Mitochondrial insertions into primate nuclear genomes suggest the use of numts as a tool for phylogeny. Jul 2009
• The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome. 29 Jun 2009
• Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis. 14 Jun 2009
• Mapping barley Ds insertions using wheat deletion lines reveals high insertion frequencies in gene-rich regions with high to moderate recombination rates. 30 May 2009
• Expression level of ABERRANT PANICLE ORGANIZATION1 determines rice inflorescence form through control of cell proliferation in the meristem. 20 Apr 2009
• Transcriptional enhancers induce insertional gene deregulation independently from the vector type and design. 15 Mar 2009
• Identification of the CLCN7 gene mutations in two Chinese families with autosomal dominant osteopetrosis (type II). 12 Mar 2009
• Angiotensin I-converting enzyme I/D polymorphism and suicidal behaviors. 3 Mar 2009
• Candidate gene strategy reveals ENAM mutations. 27 Feb 2009
• ACE D/I polymorphism, migraine, and cardiovascular disease in women. 15 Feb 2009
• Rare mutations of FGFR2 causing apert syndrome: identification of the first partial gene deletion, and an Alu element insertion from a new subfamily. 30 Jan 2009
• Association of angiotensin-converting enzyme insertion/deletion polymorphism with obesity, cardiovascular risk factors and exercise-mediated changes in Korean women. 4 Jan 2009
• A novel loss-of-function mutation in the GNS gene causes Sanfilippo syndrome type D. 30 Dec 2008
• Site-specific modification of the bovine genome using Cre recombinase-mediated gene targeting. 30 Dec 2008
• A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with risk of coal workers' pneumoconiosis. 30 Dec 2008
• Insertion and deletion events that define the pathogen Mycobacterium avium subsp. paratuberculosis. 19 Nov 2008

See a longer list of these articles.

Technical information about 'Mutagenesis, Insertional'

Definition: Mutagenesis where the mutation is caused by the introduction of foreign DNA sequences into a gene or extragenic sequence. This may occur spontaneously in vivo or be experimentally induced in vivo or in vitro. Proviral DNA insertions into or adjacent to a cellular proto-oncogene can interrupt GENETIC TRANSLATION of the coding sequences or interfere with recognition of regulatory elements and cause unregulated expression of the proto-oncogene resulting in tumor formation.

Descriptor UI: D016254

Alternative terms: Mutagenesis, Insertional; Insertional Mutagenesis; Sequence Insertion; Insertion, Sequence; Insertions, Sequence; Sequence Insertions; Viral Insertional Mutagenesis; Insertional Mutagenesis, Viral; Mutagenesis, Viral Insertional; Linker-Insertion Mutagenesis; Linker Insertion Mutagenesis; Mutagenesis, Linker-Insertion; Gene Insertion; Gene Insertions; Insertion, Gene; Insertions, Gene; Insertion Mutation; Insertion Mutations; Mutation, Insertion; Mutations, Insertion; Insertional Activation; Activation, Insertional; Activations, Insertional; Insertional Activations; Mutagenesis, Cassette; Cassette Mutagenesis;

Related Mesh Headings: DNA Transposable Elements;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; economics; history; instrumentation; methods; statistics & numerical data; standards; utilization;

Tree Number: E05.393.420.601.550; G05.355.600.550; G05.365.590.575;

History Note: 91