Mutagenesis
Research News and Information

Monday, November 23, 2009

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10.

21 Oct 2009 The metalloproteinases TACE [tumour necrosis factor alpha-converting enzyme; also known as ADAM17 (a disintegrin and metalloproteinase 17)] and ADAM10 are the primary enzymes responsible for catalysing release of membrane-anchored proteins from the ... Read more...

In vivo role of a potassium channel-binding protein in regulating neuronal excitability and behavior.

19 Oct 2009 Molecular details of ion channel interactions with modulatory subunits have been investigated widely in transfected cells, but the physiological roles of ion channel modulatory protein complexes in native neurons remain largely unexplored. The ... Read more...

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.

6 Oct 2009 Recent advances in next generation sequencing have made it possible to precisely characterize all somatic coding mutations that occur during the development and progression of individual cancers. Here we used these approaches to sequence the genomes ... Read more...

Latest indexed articles for 'Mutagenesis'

These are the very latest articles for this heading:

• Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10. 21 Oct 2009
• In vivo role of a potassium channel-binding protein in regulating neuronal excitability and behavior. 19 Oct 2009
• Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. 6 Oct 2009
• A Rubisco mutant that confers growth under a normally "inhibitory" oxygen concentration. 27 Sep 2009
• Cytochrome c4 can be involved in the photosynthetic electron transfer system in the purple bacterium Rubrivivax gelatinosus. 27 Sep 2009
• Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor. 26 Sep 2009
• Evolutionary replacement of UV vision by violet vision in fish. 26 Sep 2009
• Association of Merkel cell polyomavirus-specific antibodies with Merkel cell carcinoma. 21 Sep 2009
• Simultaneous improvement of catalytic activity and thermal stability of tyrosine phenol-lyase by directed evolution. 21 Sep 2009
• Reconstitution and engineering of apoptotic protein interactions on the bacterial cell surface. 15 Sep 2009
• Assessment of three Resistance-Nodulation-Cell Division drug efflux transporters of Burkholderia cenocepacia in intrinsic antibiotic resistance. 15 Sep 2009
• Following evolutionary paths to protein-protein interactions with high affinity and selectivity. 11 Sep 2009
• RelB and RelE of Escherichia coli form a tight complex that represses transcription via the ribbon-helix-helix motif in RelB. 6 Sep 2009
• Three discontinuous loop nucleotides in the 3' terminal stem-loop are required for Red clover necrotic mosaic virus RNA-2 replication. 3 Sep 2009
• Trans-cis switching mechanisms in proline analogues and their relevance for the gating of the 5-HT3 receptor. Sep 2009
• Light-dependent roles of the G-protein alpha subunit GNA1 of Hypocrea jecorina (anamorph Trichoderma reesei). Sep 2009
• Mutagenesis studies toward understanding allostery in thrombin. 30 Aug 2009
• Design of a novel heme protein with a non-heme globin scaffold. 30 Aug 2009
• Taking the chemical out of chemical genetics. 30 Aug 2009
• Role of the ArcAB two-component system in the resistance of Escherichia coli to reactive oxygen stress. 26 Aug 2009

See a longer list of these articles.

Technical information about 'Mutagenesis'

Definition: Process of generating a genetic MUTATION. It may occur spontaneously or be induced by MUTAGENS.

Descriptor UI: D016296

Alternative terms: Mutagenesis; Mutageneses;

Related Mesh Headings: Mutagens; Antimutagenic Agents;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G05.355.600;

History Note: 91