Myelopoiesis - Drug effects
Research News and Information

Monday, November 23, 2009

Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor.

13 Dec 2009 We describe an infant with cytomegalovirus (CMV) infection presenting as transient myeloproliferation resembling juvenile myelomonocytic leukemia (JMML). The patient fulfilled the international diagnostic criteria of JMML, including hypersensitivity ... Read more...

M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.

6 Jul 2009 The role of hematopoietic cytokines in lineage commitment remains uncertain. To gain insight into the contribution of cytokine signaling to myeloid lineage specification, we compared granulocyte colony-stimulating factor (G-CSF) and macrophage ... Read more...

Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis.

28 Jan 2009 Retinoids triggers differentiation of acute promyelocytic leukemia (APL) blasts by transcriptional regulation of myeloid regulatory genes. Using a microarray approach, we have identified a novel retinoid-responsive gene (CXXC5) encoding a nuclear ... Read more...

Latest indexed articles for 'Myelopoiesis - Drug effects'

These are the very latest articles for this heading:

• Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor. 13 Dec 2009
• M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification. 6 Jul 2009
• Functional involvement of RINF, retinoid-inducible nuclear factor (CXXC5), in normal and tumoral human myelopoiesis. 28 Jan 2009
• Modulators of arginine metabolism support cancer immunosurveillance. 7 Jan 2009
• Scorpion venom peptides accelerate hematopoietic recovery of myelosuppression in irradiated mice. 30 Dec 2008
• Medium adsorbance fraction of reticulocyte and myeloperoxidase index may individuate a patient subset with a low risk of chemotherapy-related neutropenia. 30 Dec 2008
• Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function. 6 Dec 2008
• Elucidating bone marrow edema and myelopoiesis in murine arthritis using contrast-enhanced magnetic resonance imaging. 29 Jun 2008
• Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3. 9 Jun 2008
• Myeloprotection following cytotoxic damage: the sooner the better. 6 Apr 2008
• Essential role of C/EBPalpha in G-CSF-induced transcriptional activation and chromatin modification of myeloid-specific genes. 30 Mar 2008
• A role for the transcription intermediary factor 2 in zebrafish myelopoiesis. 2 Mar 2008
• Comparative studies of the effects of Tabebuia avellanedae bark extract and beta-lapachone on the hematopoietic response of tumour-bearing mice. 6 Feb 2008
• Requirement of N-myristoyltransferase 1 in the development of monocytic lineage. 13 Jan 2008
• Retinoic acid signaling in myelopoiesis. 30 Dec 2007
• Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics. 16 Oct 2007
• Sustained telomere erosion due to increased stem cell turnover during triple autologous hematopoietic stem cell transplantation. 16 Oct 2007
• G-CSF control of neutrophils dynamics in the blood. 5 Jun 2007
• IL-7 induces myelopoiesis and erythropoiesis. 30 Jan 2007
• Serious, multi-organ hypersensitivity to lopinavir alone, involving cutaneous-mucous rash, and myeloid, liver, and kidney function. 26 Nov 2006

See a longer list of these articles.

Technical information about 'Myelopoiesis'

Definition: Formation of MYELOID CELLS from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via MYELOID STEM CELLS. Myelopoiesis generally refers to the production of leukocytes in blood, such as MONOCYTES and GRANULOCYTES. This process also produces precursor cells for MACROPHAGE and DENDRITIC CELLS found in the lymphoid tissue.

Descriptor UI: D038042

Alternative terms: Myelopoiesis;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G04.299.151.825.597.750; G09.188.124.544.597.750;

History Note: 2003; use LEUKOPOIESIS 1998-2002