Myelopoiesis
Research News and Information

Sunday, November 22, 2009

Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor.

13 Dec 2009 We describe an infant with cytomegalovirus (CMV) infection presenting as transient myeloproliferation resembling juvenile myelomonocytic leukemia (JMML). The patient fulfilled the international diagnostic criteria of JMML, including hypersensitivity ... Read more...

PLZF is a regulator of homeostatic and cytokine-induced myeloid development.

30 Aug 2009 A major question in hematopoiesis is how the system maintains long-term homeostasis whereby the generation of large numbers of differentiated cells is balanced with the requirement for maintenance of progenitor pools, while remaining sufficiently ... Read more...

Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output.

2 Aug 2009 The granulocyte-macrophage colony-stimulating factor (GM-CSF)/interleukin (IL)-3/IL-5 receptor family regulates the production and function of myeloid cells. These cytokines signal through receptor complexes that consist of unique ligand-binding ... Read more...

Latest indexed articles for 'Myelopoiesis'

These are the very latest articles for this heading:

• Cytomegalovirus infection mimicking juvenile myelomonocytic leukemia showing hypersensitivity to granulocyte-macrophage colony stimulating factor. 13 Dec 2009
• PLZF is a regulator of homeostatic and cytokine-induced myeloid development. 30 Aug 2009
• Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output. 2 Aug 2009
• Anchored and soluble gangliosides contribute to myelosupportivity of stromal cells. 22 Jul 2009
• Hematopoietic cytokines can instruct lineage choice. 8 Jul 2009
• M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification. 6 Jul 2009
• Mammalian target of rapamycin activity is required for expansion of CD34+ hematopoietic progenitor cells. 14 Jun 2009
• Bone and blood vessels: the hard and the soft of hematopoietic stem cell niches. 3 Jun 2009
• MAPK signaling pathways in the regulation of hematopoiesis. 2 Jun 2009
• The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms. 27 May 2009
• C/EBPalpha initiates primitive myelopoiesis in pluripotent embryonic cells. 4 May 2009
• Enhanced expression of FHL2 leads to abnormal myelopoiesis in vivo. 14 Apr 2009
• CREB in the pathophysiology of cancer: implications for targeting transcription factors for cancer therapy. 5 Apr 2009
• The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domains. 31 Mar 2009
• Different clinical importance of FLT3 internal tandem duplications in AML according to FAB classification: possible existence of distinct leukemogenesis involving monocyte differentiation pathway. 17 Mar 2009
• Gfi1 regulates miR-21 and miR-196b to control myelopoiesis. 8 Mar 2009
• Transcriptional regulation of a myeloid-lineage specific gene lysozyme C during zebrafish myelopoiesis. 7 Mar 2009
• Prenatal diagnosis of transient abnormal myelopoiesis in a Down syndrome fetus. Mar 2009
• NA-Seq: a discovery tool for the analysis of chromatin structure and dynamics during differentiation. 27 Feb 2009
• Myeloid-derived suppressor cells as regulators of the immune system. 27 Feb 2009

See a longer list of these articles.

Technical information about 'Myelopoiesis'

Definition: Formation of MYELOID CELLS from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via MYELOID STEM CELLS. Myelopoiesis generally refers to the production of leukocytes in blood, such as MONOCYTES and GRANULOCYTES. This process also produces precursor cells for MACROPHAGE and DENDRITIC CELLS found in the lymphoid tissue.

Descriptor UI: D038042

Alternative terms: Myelopoiesis;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G04.299.151.825.597.750; G09.188.124.544.597.750;

History Note: 2003; use LEUKOPOIESIS 1998-2002