Myocardial Reperfusion Injury - Pathology
Research News and Information

Sunday, November 22, 2009

Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion.

30 Oct 2009 BACKGROUND: Methadone is an opioid agonist often given to manage acute and chronic pain. We sought to determine whether methadone compared with morphine dose dependently reduces myocardial infarct size (IS) and whether the mechanism is delta-opioid ... Read more...

Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion.

13 Sep 2009 BACKGROUND: Hypercholesterolemia is prevalent in patients who experience myocardial ischemia-reperfusion injury (IR). We investigate the impact of dietary-induced hypercholesterolemia on the myocardium in the setting of acute IR. METHODS AND ... Read more...

Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite.

2 Sep 2009 The aim of the present study was to investigate if hyperlipidemia interferes with the infarct size-limiting effect of postconditioning and to study the involvement of peroxynitrite in this phenomenon. Rats were fed a 2% cholesterol-enriched or ... Read more...

Latest indexed articles for 'Myocardial Reperfusion Injury - Pathology'

These are the very latest articles for this heading:

• Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion. 30 Oct 2009
• Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion. 13 Sep 2009
• Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite. 2 Sep 2009
• O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death. 2 Sep 2009
• Gap junctions mediate the spread of ischemia-reperfusion injury. 30 Aug 2009
• GAP-134 ([2S,4R]-1-[2-aminoacetyl]4-benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs. 30 Aug 2009
• Administration of bovine polymerized haemoglobin before and during coronary occlusion reduces infarct size in rabbits. 24 Aug 2009
• Bax distribution into mitochondrial detergent-resistant microdomains is related to ceramide and cholesterol content in postischemic hearts. 18 Aug 2009
• Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. 12 Aug 2009
• Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion. 12 Aug 2009
• Pharmacological activation of soluble guanylate cyclase protects the heart against ischemic injury. 8 Aug 2009
• Ischemia and reperfusion-induced arrhythmias: role of hyperoxic preconditioning. 30 Jul 2009
• Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning. 29 Jul 2009
• Protective effects of caspase-9 and poly(ADP-ribose) polymerase inhibitors on ischemia-reperfusion-induced myocardial injury. 29 Jul 2009
• Lack of cardioprotection from subcutaneously and preischemic administered liraglutide in a closed chest porcine ischemia reperfusion model. 21 Jul 2009
• Autophagy in ischemic preconditioning and hibernating myocardium. 21 Jul 2009
• Insulin inhibits leukocyte-endothelium adherence via an Akt-NO-dependent mechanism in myocardial ischemia/reperfusion. 14 Jul 2009
• Application of zinc-bis-(DL-hydrogensaspartate) does not reduce apoptotic cell death in myocardial infarction in the rat heart. 13 Jul 2009
• Comparison of isoflurane-, sevoflurane-, and desflurane-induced pre- and postconditioning against myocardial infarction in mice in vivo. 11 Jul 2009
• Ischemia enhances translocation of connexin43 and gap junction intercellular communication, thereby propagating contraction band necrosis after reperfusion. 7 Jul 2009

See a longer list of these articles.

Technical information about 'Myocardial Reperfusion Injury'

Definition: Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.

Descriptor UI: D015428

Alternative terms: Myocardial Reperfusion Injury; Injuries, Myocardial Reperfusion; Myocardial Reperfusion Injuries; Reperfusion Injuries, Myocardial; Reperfusion Injury, Myocardial; Injury, Myocardial Reperfusion; Myocardial Ischemic Reperfusion Injury;

Related Mesh Headings: Myocardial Reperfusion; Myocardial Stunning;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C14.280.238.615; C14.280.647.625; C14.907.585.625; C14.907.725.600; C23.550.767.877.500;

History Note: 89