Myocardial Reperfusion Injury
Research News and Information

Sunday, November 22, 2009

Aprotinin abolishes sevoflurane postconditioning by inhibiting nitric oxide production and phosphorylation of protein kinase C-delta and glycogen synthase kinase 3beta.

30 Oct 2009 BACKGROUND: It remains controversial whether aprotinin use during cardiac surgery is cardioprotective or detrimental. In contrast, volatile anesthetics may offer cardioprotection perioperatively. Increased nitric oxide, protein kinase C activation, ... Read more...

Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion.

30 Oct 2009 BACKGROUND: Methadone is an opioid agonist often given to manage acute and chronic pain. We sought to determine whether methadone compared with morphine dose dependently reduces myocardial infarct size (IS) and whether the mechanism is delta-opioid ... Read more...

Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury.

3 Oct 2009 BACKGROUND: Transforming growth factor-beta family cytokines have diverse actions in the maintenance of cardiac homeostasis. Activin A is a member of this family whose regulation and function in heart are not well understood at a molecular level. ... Read more...

Latest indexed articles for 'Myocardial Reperfusion Injury'

These are the very latest articles for this heading:

• Aprotinin abolishes sevoflurane postconditioning by inhibiting nitric oxide production and phosphorylation of protein kinase C-delta and glycogen synthase kinase 3beta. 30 Oct 2009
• Acute methadone treatment reduces myocardial infarct size via the delta-opioid receptor in rats during reperfusion. 30 Oct 2009
• Activin A and follistatin-like 3 determine the susceptibility of heart to ischemic injury. 3 Oct 2009
• Ranolazine, an antianginal agent, markedly reduces ventricular arrhythmias induced by ischemia and ischemia-reperfusion. 16 Sep 2009
• Phosphodiesterase-5 inhibitor, tadalafil, protects against myocardial ischemia/reperfusion through protein-kinase g-dependent generation of hydrogen sulfide. 13 Sep 2009
• Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion. 13 Sep 2009
• Reactive oxygen species-induced stimulation of 5'AMP-activated protein kinase mediates sevoflurane-induced cardioprotection. 13 Sep 2009
• Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling. 13 Sep 2009
• Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin. 9 Sep 2009
• Novel small interfering RNA-containing solution protecting donor organs in heart transplantation. 6 Sep 2009
• Of mice and men (and effects of gene silencing). 6 Sep 2009
• Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite. 2 Sep 2009
• O-GlcNAc signaling attenuates ER stress-induced cardiomyocyte death. 2 Sep 2009
• Detection of endogenous acetylcholine release during brief ischemia in the rabbit ventricle: a possible trigger for ischemic preconditioning. 31 Aug 2009
• Gap junctions mediate the spread of ischemia-reperfusion injury. 30 Aug 2009
• Enhancement of amlodipine cardioprotection by quercetin in ischaemia/reperfusion injury in rats. 30 Aug 2009
• Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion. 30 Aug 2009
• GAP-134 ([2S,4R]-1-[2-aminoacetyl]4-benzamidopyrrolidine-2-carboxylic acid) prevents spontaneous ventricular arrhythmias and reduces infarct size during myocardial ischemia/reperfusion injury in open-chest dogs. 30 Aug 2009
• Effect of p38 MAP kinases on contractility and ischemic injury in intact heart. 30 Aug 2009
• A comparison of volatile and non volatile agents for cardioprotection during on-pump coronary surgery. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Myocardial Reperfusion Injury'

Definition: Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.

Descriptor UI: D015428

Alternative terms: Myocardial Reperfusion Injury; Injuries, Myocardial Reperfusion; Myocardial Reperfusion Injuries; Reperfusion Injuries, Myocardial; Reperfusion Injury, Myocardial; Injury, Myocardial Reperfusion; Myocardial Ischemic Reperfusion Injury;

Related Mesh Headings: Myocardial Reperfusion; Myocardial Stunning;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C14.280.238.615; C14.280.647.625; C14.907.585.625; C14.907.725.600; C23.550.767.877.500;

History Note: 89