Narcolepsy - Drug therapy
Research News and Information

Monday, November 23, 2009

[Narcolepsy and other hypersomnias]

6 Oct 2009 BACKGROUND: Narcolepsy is currently categorized into three groups; narcolepsy with and without emotionally triggered loss of muscle tone (cataplexy), and narcolepsy secondary to other medical conditions. Many patients with hypersomnia are diagnosed ... Read more...

Armodafinil.

30 Aug 2009 Armodafinil is the R-enantiomer of modafinil, a wake-promoting agent, that primarily affects areas of the brain involved in controlling wakefulness. Once-daily armodafinil was effective in improving wakefulness in adult patients with excessive ... Read more...

Animal models of narcolepsy.

30 Jul 2009 Narcolepsy is a debilitating sleep disorder with excessive daytime sleepiness and cataplexy as its two major symptoms. Although this disease was first described about one century ago, an animal model was not available until the 1970s. With the ... Read more...

Latest indexed articles for 'Narcolepsy - Drug therapy'

These are the very latest articles for this heading:

• Normalization of hypocretin-1 in narcolepsy after intravenous immunoglobulin treatment. 18 Oct 2009
• [Narcolepsy and other hypersomnias] 6 Oct 2009
• Armodafinil. 30 Aug 2009
• Animal models of narcolepsy. 30 Jul 2009
• The hypocretins and their role in narcolepsy. 30 Jul 2009
• Neuroimaging of narcolepsy. 30 Jul 2009
• The sleep-wake cycle, the hypocretin/orexin system and narcolepsy: advances from preclinical research to treatment. 30 Jul 2009
• Hallucinations associated with modafinil treatment for narcolepsy. 30 Jul 2009
• Nail-gun narcolepsy. 16 Jul 2009
• Narcolepsy: action of two gamma-aminobutyric acid type B agonists, baclofen and sodium oxybate. 29 Jun 2009
• [Recent advance of treatments for narcolepsy and hypersomnia] 30 May 2009
• Differential effects of acute and repeat dosing with the H3 antagonist GSK189254 on the sleep-wake cycle and narcoleptic episodes in Ox-/- mice. 29 Apr 2009
• Narcolepsy--master of disguise: evidence-based recommendations for management. 29 Apr 2009
• Treatment with venlafaxine in six cases of children with narcolepsy and with cataplexy and hypnagogic hallucinations. 30 Mar 2009
• Xyrem safety: the debate continues. 19 Mar 2009
• Three deaths associated with use of Xyrem. 7 Mar 2009
• Biomedical application of orexin/hypocretin receptor ligands in neuroscience. 24 Feb 2009
• Psychological health in central hypersomnias: the French Harmony study. 9 Feb 2009
• CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome. 30 Jan 2009
• A multi-drug intoxication fatality involving Xyrem (GHB). 27 Jan 2009

See a longer list of these articles.

Technical information about 'Narcolepsy'

Definition: A condition characterized by recurrent episodes of daytime somnolence and lapses in consciousness (microsomnias) that may be associated with automatic behaviors and AMNESIA. CATAPLEXY; SLEEP PARALYSIS, and hypnagogic HALLUCINATIONS frequently accompany narcolepsy. The pathophysiology of this disorder includes sleep-onset rapid eye movement (REM) sleep, which normally follows stage III or IV sleep. (From Neurology 1998 Feb;50(2 Suppl 1):S2-S7)

Descriptor UI: D009290

Alternative terms: Narcolepsy; Narcoleptic Syndrome; Narcoleptic Syndromes; Syndrome, Narcoleptic; Syndromes, Narcoleptic; Gelineau's Syndrome; Gelineau's Syndromes; Gelineaus Syndrome; Syndrome, Gelineau's; Syndromes, Gelineau's; Gelineau Syndrome; Syndrome, Gelineau; Paroxysmal Sleep; Sleep, Paroxysmal; Narcolepsy-Cataplexy Syndrome; Narcolepsy Cataplexy Syndrome; Narcolepsy-Cataplexy Syndromes; Syndrome, Narcolepsy-Cataplexy; Syndromes, Narcolepsy-Cataplexy;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.886.425.800.200.750; F03.870.400.800.200.750;

History Note: 67(63)