Necrosis
Research News and Information

Sunday, November 22, 2009

Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death.

29 Nov 2009 Our previous studies have shown that brain-derived neurotrophic factor (BDNF) enhances bone/cementum-related protein gene expression through the TrkB-c-Raf-ERK1/2-Elk-1 signaling pathway in cementoblasts, which play a critical role in the ... Read more...

Growth inhibition of bovine pulmonary artery smooth muscle cells following long-term heparin treatment.

29 Nov 2009 Heparin (HP) inhibits pulmonary artery smooth muscle cell (PASMC) growth in vitro and vascular remodeling in vivo. Bârzu et al. (1994) suggested that the antiproliferative effect of HP on rat aortic smooth muscle cell in vitro diminishes with ... Read more...

VEGF expression as a prognostic marker in osteosarcoma.

29 Nov 2009 BACKGROUND: The vascular endothelial growth factor (VEGF) pathway is the key regulator of angiogenesis. In osteosarcoma baseline VEGF is of proven prognostic value but prognostic potential of post-NACT VEGF expression is largely unexplored. ... Read more...

Latest indexed articles for 'Necrosis'

These are the very latest articles for this heading:

• Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death. 29 Nov 2009
• Growth inhibition of bovine pulmonary artery smooth muscle cells following long-term heparin treatment. 29 Nov 2009
• VEGF expression as a prognostic marker in osteosarcoma. 29 Nov 2009
• Bevacizumab as therapy for radiation necrosis in four children with pontine gliomas. 13 Nov 2009
• Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning? 30 Oct 2009
• The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion. 30 Oct 2009
• Case records of the Massachusetts General Hospital. Case 33-2009. A 35-year-old woman with fever, abdominal pain, and hypotension after cesarean section. 20 Oct 2009
• Painful oral ulcerations in a 51-year-old woman. 13 Oct 2009
• Cell death. 13 Oct 2009
• Inhibition of constitutive and cxc-chemokine-induced NF-kappaB activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells. 4 Oct 2009
• Induction of autophagy by spermidine promotes longevity. 2 Oct 2009
• Chronic necrotizing pulmonary aspergillosis or invasive pulmonary aspergillosis. 29 Sep 2009
• Effect of biliary tract external drainage on cytokine expression and histomorphology of intestine, liver, and lung in rats with hemorrhagic shock. 29 Sep 2009
• Pathology in practice. Severe multifocal to locally extensive, monophasic skeletal muscle necrosis and multifocal, monophasic myocardial necrosis. 29 Sep 2009
• Astrocytes are more resistant to focal cerebral ischemia than neurons and die by a delayed necrosis. 29 Sep 2009
• Cytotoxicity of nanoparticles independent from oxidative stress. 29 Sep 2009
• Prophylactic effect of clarithromycin in skin flap complications in cochlear implants surgery. 29 Sep 2009
• A novel murine model for localized radiation necrosis and its characterization using advanced magnetic resonance imaging. 29 Sep 2009
• Eosinophils oxidize damage-associated molecular pattern molecules derived from stressed cells. 28 Sep 2009
• Images in clinical medicine. Uvular necrosis after endoscopy. 15 Sep 2009

See a longer list of these articles.

Technical information about 'Necrosis'

Definition: The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. Distinguish it from APOPTOSIS which is a normal, regulated cellular process.

Descriptor UI: D009336

Alternative terms: Necrosis; Necroses;

Related Mesh Headings: Tumor Necrosis Factor-alpha; Apoptosis;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C23.550.717; G04.299.139.638;

Technical Notes: IM for general or for necrotic process; necrosis in an organ or tissue: index organ or tissue /pathol (IM) + NECROSIS (NIM); note specific necrosis terms; radionecrosis: index RADIATION INJURIES/pathol (IM) + organ /pathol (IM) + NECROSIS (NIM)