Neocortex
Research News and Information

Sunday, November 22, 2009

Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres.

30 Oct 2009 Down's syndrome neurophenotypes are characterized by mental retardation and a decreased brain volume. To identify whether deficits in proliferation could be responsible for this phenotype, neural progenitor cells were isolated from the developing ... Read more...

Gene expression analysis on anterior temporal neocortex of patients with intractable epilepsy.

30 Oct 2009 To elucidate the molecular basis of intractable epilepsy (IE), we used a whole-genome transcriptomic approach to identify genes involved in the pathogenesis of this disease. Using a complementary DNAs microarray representing 4096 human genes, we ... Read more...

Propofol inhibits aquaporin 4 expression through a protein kinase C-dependent pathway in an astrocyte model of cerebral ischemia/reoxygenation.

30 Oct 2009 BACKGROUND: Aquaporin 4 (AQP4) plays a key role in maintaining water balance in the central nervous system, and its dysfunction may lead to brain edema. Previous studies have suggested that propofol may be involved in neuroprotection by preventing ... Read more...

Latest indexed articles for 'Neocortex'

These are the very latest articles for this heading:

• Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres. 30 Oct 2009
• Gene expression analysis on anterior temporal neocortex of patients with intractable epilepsy. 30 Oct 2009
• Propofol inhibits aquaporin 4 expression through a protein kinase C-dependent pathway in an astrocyte model of cerebral ischemia/reoxygenation. 30 Oct 2009
• Evolution of the neocortex: a perspective from developmental biology. 29 Sep 2009
• Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. 14 Sep 2009
• Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. 8 Sep 2009
• Polycomb limits the neurogenic competence of neural precursor cells to promote astrogenic fate transition. 8 Sep 2009
• Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome. 7 Sep 2009
• Cooperative synapse formation in the neocortex. 2 Sep 2009
• Internally mediated developmental desynchronization of neocortical network activity. 31 Aug 2009
• Surgical treatment of the extratemporal epilepsies. 30 Aug 2009
• Treatment algorithms in refractory partial epilepsy. 30 Aug 2009
• Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? 24 Aug 2009
• Caloric restriction attenuates amyloid deposition in middle-aged dtg APP/PS1 mice. 18 Aug 2009
• Neocortical networks entrain neuronal circuits in cerebellar cortex. 17 Aug 2009
• beta1 integrin maintains integrity of the embryonic neocortical stem cell niche. 16 Aug 2009
• Possible promotion of neuronal differentiation in fetal rat brain neural progenitor cells after sustained exposure to static magnetism. 13 Aug 2009
• Microarray analyses reveal regional astrocyte heterogeneity with implications for neurofibromatosis type 1 (NF1)-regulated glial proliferation. 13 Aug 2009
• Behavioral tagging is a general mechanism of long-term memory formation. 9 Aug 2009
• Regional rates of neocortical atrophy from normal aging to early Alzheimer disease. 9 Aug 2009

See a longer list of these articles.

Technical information about 'Neocortex'

Definition: The largest portion of the CEREBRAL CORTEX. It is composed of NEURONS arranged in six layers.

Descriptor UI: D019579

Alternative terms: Neocortex; Neocortices;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.730.885.287.500.420;

History Note: 98