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Neoplasms - Immunology
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Definition of 'Neoplasms'

New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Common names: Neoplasms; Neoplasm; Tumors; Tumor; Benign Neoplasms; Neoplasms, Benign; Benign Neoplasm; Neoplasm, Benign; Cancer; Cancers

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Monday, November 23, 2009

The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells.

13 Nov 2009 Cyclin-A2, a key cell cycle regulator, has been shown to be overexpressed in various types of malignancies with little expression in normal tissue. Such tumor-associated genes potentially are useful targets for cancer immunotherapy. However, ... Read more...


Cancer risk evaluation in psoriasis: in search of the Holy Grail?

30 Oct 2009 Benefit-risk assessment of systemic treatment in psoriasis is a dynamic process. Long-term safety of psoriasis therapies has been questioned, with the spectrum of systemic immunosuppression potentially leading to increased cancer risk. In this ... Read more...


STATs in cancer inflammation and immunity: a leading role for STAT3.

30 Oct 2009 Commensurate with their roles in regulating cytokine-dependent inflammation and immunity, signal transducer and activator of transcription (STAT) proteins are central in determining whether immune responses in the tumour microenvironment promote or ... Read more...

 

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Technical information about 'Neoplasms'

Definition: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Descriptor UI: D009369

Alternative terms: Neoplasms; Neoplasm; Tumors; Tumor; Benign Neoplasms; Neoplasms, Benign; Benign Neoplasm; Neoplasm, Benign; Cancer; Cancers;

Related Mesh Headings: Antibodies, Neoplasm; Antigens, Neoplasm; Antineoplastic Agents; Carcinogens; DNA, Neoplasm; Oncogenic Viruses; Precancerous Conditions; RNA, Neoplasm; Pleural Effusion, Malignant; Genes, Tumor Suppressor; Anticarcinogenic Agents;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04;

Online Note: pre-explosion = NEOPLASMS (PX)

History Note: /diagnosis was NEOPLASM DIAGNOSIS 1964-65; /etiology was NEOPLASM ETIOLOGY 1964-65; /immunology was NEOPLASM IMMUNOLOGY 1964-65; /radiotherapy was NEOPLASM RADIOTHERAPY 1964-65; /therapy was NEOPLASM THERAPY 1964-65; NEOPLASM STATISTICS was heading 1964-65; CARCINOGENESIS was heading 1977

Technical Notes: avoid: too general; prefer specifics; policy: Manual section 24; /chem ind permitted but consider also CARCINOGENS; /class: consider also NEOPLASM STAGING (see note there) but "grading" = /pathol; /etiol: consider also ONCOGENIC VIRUSES; /vet: Manual 24.6+ or TN 136; TN 135: MeSH terms for neoplasms classed by tissue; /drug ther: consider also ANTINEOPLASTIC AGENTS & its specifics; /genet: consider also GENES, TUMOR SUPPRESSOR /immunol: consider also TUMOR ESCAPE; consider also ANTIGENS, NEOPLASM & ANTIBODIES, NEOPLASM; /microbiol: consider also ONCOGENIC VIRUSES; /nurs = the patient, ONCOLOGIC NURSING = the oncologic specialty; /prev: consider also ANTICARCINOGENIC AGENTS; /radiother = the patient, RADIATION ONCOLOGY = the specialty; consider also BRACHYTHERAPY; /second = NEOPLASM METASTASIS but do not confuse with NEOPLASMS, SECOND PRIMARY; familial: consider also NEOPLASTIC SYNDROMES, HEREDITARY; metastatic cancer of unknown origin: index under NEOPLASM METASTASIS; Tumor Key: TN Suppl

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